The nasal route has been used for many years for the local treatment of nasal diseases.
More recently, this route has been gaining momentum, due to the possibility of targeting the …

Studies on the development of drug delivery systems have increased because these
systems have particular characteristics that allow them to improve therapeutics. Among …

Nose-to-brain drug delivery has been of great interest for the treatment of many central
nervous system (CNS) diseases and psychiatric disorders over past decades. Several …

Background: Current treatments for neurodegenerative diseases are challenging, due to the
absence of fully effective medicines. One of the major problems associated to these is the …

The management of the central nervous system (CNS) disorders is challenging, due to the
need of drugs to cross the blood‒brain barrier (BBB) and reach the brain. Among the …

Introduction: The blood brain barrier is a functional barrier allowing the entry into the brain of
only essential nutrients, excluding other molecules. Its structure, although essential to keep …

The exponential growth of nanotechnology has focused on therapeutic pursuits, notably for
brain disorders. Nanocarriers have submicron particle sizes, typically around 500 nm. Over …

Central nervous system disorders significantly affect the lives and health of millions of
people worldwide. Despite many therapeutic drugs are available that could potentially target …

Addressing disorders related to the central nervous system (CNS) remains a complex
challenge because of the presence of the blood-brain barrier (BBB), which restricts the entry …

Background: Nanostructured lipid carriers (NLCs) are in high demand in the existing
pharmaceutical domain due to its high versatility. It is the newer generation of lipid …