Dynamics of blood flow and oxygenation changes during brain activation: the balloon model

RB Buxton, EC Wong, LR Frank - Magnetic resonance in …, 1998 - Wiley Online Library
A biomechanical model is presented for the dynamic changes in deoxyhemoglobin content
during brain activation. The model incorporates the conflicting effects of dynamic changes in …

[HTML][HTML] Comparing hemodynamic models with DCM

KE Stephan, N Weiskopf, PM Drysdale, PA Robinson… - Neuroimage, 2007 - Elsevier
The classical model of blood oxygen level-dependent (BOLD) responses by Buxton et
al.[Buxton, RB, Wong, EC, Frank, LR, 1998. Dynamics of blood flow and oxygenation …

Modeling the hemodynamic response to brain activation

RB Buxton, K Uludağ, DJ Dubowitz, TT Liu - Neuroimage, 2004 - Elsevier
Neural activity in the brain is accompanied by changes in cerebral blood flow (CBF) and
blood oxygenation that are detectable with functional magnetic resonance imaging (fMRI) …

Dynamic models of BOLD contrast

RB Buxton - Neuroimage, 2012 - Elsevier
This personal recollection looks at the evolution of ideas about the dynamics of the blood
oxygenation level dependent (BOLD) signal, with an emphasis on the balloon model. From …

Oscillations in cerebral haemodynamics: Implications for functional activation studies

CE Elwell, R Springett, E Hillman, DT Delpy - Oxygen transport to tissue …, 1999 - Springer
The blood oxygenation level dependent (BOLD) contrast signal in functional magnetic
resonance imaging (fMRI) provides highly spatially resolved deoxygenation maps of the …

Investigation of BOLD signal dependence on cerebral blood flow and oxygen consumption: the deoxyhemoglobin dilution model

RD Hoge, J Atkinson, B Gill, GR Crelier… - … in Medicine: An …, 1999 - Wiley Online Library
The relationship between blood oxygenation level‐dependent (BOLD) MRI signals, cerebral
blood flow (CBF), and oxygen consumption (CMRO2) in the physiological steady state was …

Coupling of cerebral blood flow and oxygen consumption during physiological activation and deactivation measured with fMRI

K Uludağ, DJ Dubowitz, EJ Yoder, K Restom, TT Liu… - Neuroimage, 2004 - Elsevier
The physiological basis of the blood oxygenation level dependent (BOLD) signal and its
dependence on baseline cerebral blood flow (CBF) were investigated by comparing …

The physics of functional magnetic resonance imaging (fMRI)

RB Buxton - Reports on Progress in Physics, 2013 - iopscience.iop.org
Functional magnetic resonance imaging (fMRI) is a methodology for detecting dynamic
patterns of activity in the working human brain. Although the initial discoveries that led to …

A generalized procedure for calibrated MRI incorporating hyperoxia and hypercapnia

CJ Gauthier, RD Hoge - Human brain mapping, 2013 - Wiley Online Library
Calibrated MRI techniques use the changes in cerebral blood flow (CBF) and blood
oxygenation level‐dependent (BOLD) signal evoked by a respiratory manipulation to …

Increased oxygen consumption following activation of brain: theoretical footnotes using spectroscopic data from barrel cortex

J Mayhew, D Johnston, J Martindale, M Jones… - Neuroimage, 2001 - Elsevier
Optical imaging spectroscopy (OIS) and laser Doppler flowmetry (LDF) data sequences from
anesthetized rats were used to determine the relationship between changes in oxy-and …