Antimicrobial peptide engineering: rational design, synthesis, and synergistic effect
N Jongruja - Russian Journal of Bioorganic Chemistry, 2020 - Springer
The swift killing kinetics is an attractive characteristics of wide-spectrum antimicrobial activity
of peptides, which made them generate great attention as possible antitoxin pharmaceutics …
of peptides, which made them generate great attention as possible antitoxin pharmaceutics …
Synthetic molecular evolution of antimicrobial peptides
Highlights•Various peptide design methods have facilitated peptide–drug
development.•Only a few peptide therapeutics have entered the antibiotic market in the past …
development.•Only a few peptide therapeutics have entered the antibiotic market in the past …
Computer aided design of non-toxic antibacterial peptides
P Rondon-Villarreal… - Current topics in medicinal …, 2018 - ingentaconnect.com
Antimicrobial resistance is increasing at an alarming rate and the number of new antibiotics
developed and approved has decreased in the last decades, basically for economic and …
developed and approved has decreased in the last decades, basically for economic and …
Rational design of artificial β-strand-forming antimicrobial peptides with biocompatible properties
K Rapsch, FF Bier… - Molecular …, 2014 - ACS Publications
Because the intensive use of antibiotics has led to a large variety of resistant bacterial
strains, therapeutic measures have become increasingly challenging. In order to ensure …
strains, therapeutic measures have become increasingly challenging. In order to ensure …
In vitro activity of novel in silico‐developed antimicrobial peptides against a panel of bacterial pathogens
AA Romani, MC Baroni, S Taddei… - Journal of Peptide …, 2013 - Wiley Online Library
Antimicrobial‐peptide‐based therapies could represent a reliable alternative to overcome
antibiotic resistance, as they offer potential advantages such as rapid microbicidal activity …
antibiotic resistance, as they offer potential advantages such as rapid microbicidal activity …
[PDF][PDF] Rational development of antimicrobial peptides for therapeutic use: design and production of highly active compounds
The emergence of drug-resistant pathogenic microbial strains has created an urgent need
for new anti-infective molecule development. In order to avoid the spread of bacterial …
for new anti-infective molecule development. In order to avoid the spread of bacterial …
Biosynthesis of antimicrobial peptides and its medical application
WEI Daixu, G Hailun - Synthetic Biology Journal, 2022 - synbioj.cip.com.cn
Due to their broad-spectrum antibacterial activity and low incidence of drug resistance,
natural antimicrobial peptides have become a potential alternative to antibiotics. In addition …
natural antimicrobial peptides have become a potential alternative to antibiotics. In addition …
Lights and shadows on the therapeutic use of antimicrobial peptides
D Bellotti, M Remelli - Molecules, 2022 - mdpi.com
The emergence of antimicrobial-resistant infections is still a major concern for public health
worldwide. The number of pathogenic microorganisms capable of resisting common …
worldwide. The number of pathogenic microorganisms capable of resisting common …
Progress and future of the computational design of antimicrobial peptides (AMPs): bio-inspired functional molecules
The effectiveness of antibiotics is greatly enhanced by their ability to target invasive
organisms involved in the ancient evolutionary battle between hosts and pathogens …
organisms involved in the ancient evolutionary battle between hosts and pathogens …
Peptides with dual antimicrobial–anticancer activity: Strategies to overcome peptide limitations and rational design of anticancer peptides
Y Liscano, J Oñate-Garzón, JP Delgado - Molecules, 2020 - mdpi.com
Peptides are naturally produced by all organisms and exhibit a wide range of physiological,
immunomodulatory, and wound healing functions. Furthermore, they can provide with …
immunomodulatory, and wound healing functions. Furthermore, they can provide with …
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