Focus on extracellular vesicles: physiological role and signalling properties of extracellular membrane vesicles

N Iraci, T Leonardi, F Gessler, B Vega… - International journal of …, 2016 - mdpi.com
Extracellular vesicles (EVs) are a heterogeneous population of secreted membrane
vesicles, with distinct biogenesis routes, biophysical properties and different functions both …

Strategies for the use of Extracellular Vesicles for the Delivery of Therapeutics

S Sil, RS Dagur, K Liao, ES Peeples, G Hu… - Journal of Neuroimmune …, 2020 - Springer
Extracellular vesicles (EVs) are nanosized, membrane-bound vesicles released from
eukaryotic and prokaryotic cells that can transport cargo containing DNA, RNA, lipids and …

Biological properties of extracellular vesicles and their physiological functions

M Yáñez-Mó, PRM Siljander, Z Andreu… - Journal of …, 2015 - Taylor & Francis
In the past decade, extracellular vesicles (EVs) have been recognized as potent vehicles of
intercellular communication, both in prokaryotes and eukaryotes. This is due to their capacity …

Subpopulations of extracellular vesicles and their therapeutic potential

C Lässer, SC Jang, J Lötvall - Molecular aspects of medicine, 2018 - Elsevier
Extracellular vesicles (EVs), such as exosomes and microvesicles, have over the last 10–15
years been recognized to convey key messages in the molecular communication between …

[HTML][HTML] Role of exosomes/microvesicles in the nervous system and use in emerging therapies

CPK Lai, XO Breakefield - Frontiers in physiology, 2012 - frontiersin.org
Extracellular membrane vesicles (EMVs) are nanometer sized vesicles, including exosomes
and microvesicles capable of transferring DNAs, mRNAs, microRNAs, non-coding RNAs …

Emerging roles of extracellular vesicles in neurodegenerative disorders

Y You, T Ikezu - Neurobiology of Disease, 2019 - Elsevier
Extracellular vesicles (EVs) are heterogeneous cell-derived membranous vesicles which
carry a large diversity of molecules such as proteins and RNA species. They are now …

Focus on extracellular vesicles: development of extracellular vesicle-based therapeutic systems

S Ohno, GPC Drummen, M Kuroda - International journal of molecular …, 2016 - mdpi.com
Many types of cells release phospholipid membrane vesicles thought to play key roles in cell-
cell communication, antigen presentation, and the spread of infectious agents. Extracellular …

Extracellular vesicles: mechanisms in human health and disease

M Malloci, L Perdomo, M Veerasamy… - Antioxidants & redox …, 2019 - liebertpub.com
Abstract Significance: Secreted extracellular vesicles (EVs) are now considered veritable
entities for diagnosis, prognosis, and therapeutics. These structures are able to interact with …

Extracellular vesicles: unique intercellular delivery vehicles

SLN Maas, XO Breakefield, AM Weaver - Trends in cell biology, 2017 - cell.com
Extracellular vesicles (EVs) are a heterogeneous collection of membrane-bound carriers
with complex cargoes including proteins, lipids, and nucleic acids. While the release of EVs …

[HTML][HTML] Extracellular vesicles: masters of intercellular communication and potential clinical interventions

JM Pitt, G Kroemer, L Zitvogel - The Journal of clinical …, 2016 - Am Soc Clin Investig
Intercellular signaling via extracellular vesicles (EVs) is an underappreciated modality of cell-
cell crosstalk that enables cells to convey packages of complex instructions to specific …