Rifampin Resistance Missed in Automated Liquid Culture System for Mycobacterium tuberculosis Isolates with Specific rpoB Mutations
L Rigouts, M Gumusboga, WB de Rijk… - Journal of clinical …, 2013 - Am Soc Microbiol
ABSTRACT WHO-endorsed phenotypic drug susceptibility testing (DST) methods for
Mycobacterium tuberculosis are assumed to be the gold standard for identifying rifampin …
Mycobacterium tuberculosis are assumed to be the gold standard for identifying rifampin …
Role of Disputed Mutations in the rpoB Gene in Interpretation of Automated Liquid MGIT Culture Results for Rifampin Susceptibility Testing of Mycobacterium …
P Miotto, AM Cabibbe, E Borroni… - Journal of clinical …, 2018 - Am Soc Microbiol
Low-level rifampin resistance associated with specific rpoB mutations (referred as
“disputed”) in Mycobacterium tuberculosis is easily missed by some phenotypic methods. To …
“disputed”) in Mycobacterium tuberculosis is easily missed by some phenotypic methods. To …
Mycobacterium tuberculosis Strains with Highly Discordant Rifampin Susceptibility Test Results
A Van Deun, L Barrera, I Bastian… - Journal of clinical …, 2009 - Am Soc Microbiol
The objectives of this study were to investigate the origin of highly discordant rifampin
(rifampicin)(RMP) drug susceptibility test results obtained for Mycobacterium tuberculosis …
(rifampicin)(RMP) drug susceptibility test results obtained for Mycobacterium tuberculosis …
Variable ability of rapid tests to detect Mycobacterium tuberculosis rpoB mutations conferring phenotypically occult rifampicin resistance
We compared the ability of commercial and non-commercial, phenotypic and genotypic
rapid drug susceptibility tests (DSTs) to detect rifampicin resistance (RR)-conferring …
rapid drug susceptibility tests (DSTs) to detect rifampicin resistance (RR)-conferring …
[HTML][HTML] Novel rapid PCR for the detection of Ile491Phe rpoB mutation of Mycobacterium tuberculosis, a rifampicin-resistance-conferring mutation undetected by …
E André, L Goeminne, A Colmant, P Beckert… - Clinical Microbiology …, 2017 - Elsevier
Objectives Neither the liquid medium-based Bactec MGIT, nor commercial molecular assays
such as the Xpert MTB/RIF and the MTBDRplus V2. 0 assays are capable of detecting up to …
such as the Xpert MTB/RIF and the MTBDRplus V2. 0 assays are capable of detecting up to …
Isolation of Mycobacterium tuberculosis Strains with a Silent Mutation in rpoB Leading to Potential Misassignment of Resistance Category
M Alonso, JJ Palacios, M Herranz… - Journal of clinical …, 2011 - Am Soc Microbiol
Our study provides an alert regarding the transmission of rifampin-susceptible strains of
Mycobacterium tuberculosis with a silent substitution in codon 514 of rpoB. Among 1,450 …
Mycobacterium tuberculosis with a silent substitution in codon 514 of rpoB. Among 1,450 …
Clinical failures associated with rpoB mutations in phenotypically occult multidrug-resistant Mycobacterium tuberculosis
DA Williamson, SA Roberts, JE Bower… - … of tuberculosis and …, 2012 - ingentaconnect.com
SETTING: Recently, Mycobacterium tuberculosis isolates have been described that test
phenotypically susceptible to rifampicin (RMP) yet harbour genotypic rpoB mutations …
phenotypically susceptible to rifampicin (RMP) yet harbour genotypic rpoB mutations …
Low-Level Rifampin Resistance and rpoB Mutations in Mycobacterium tuberculosis: an Analysis of Whole-Genome Sequencing and Drug Susceptibility Test Data in …
J Shea, TA Halse, D Kohlerschmidt… - Journal of clinical …, 2021 - Am Soc Microbiol
Rapid and reliable detection of rifampin (RIF) resistance is critical for the diagnosis and
treatment of drug-resistant and multidrug-resistant (MDR) tuberculosis. Discordant RIF …
treatment of drug-resistant and multidrug-resistant (MDR) tuberculosis. Discordant RIF …
Rapid identification of multidrug-resistant Mycobacterium tuberculosis isolates by rpoB gene scanning using high-resolution melting curve PCR analysis
AT Pietzka, A Indra, A Stöger… - Journal of …, 2009 - academic.oup.com
Abstract Background Multidrug-resistant (MDR) Mycobacterium tuberculosis poses a serious
threat to the control of tuberculosis (TB) and constitutes an increasing public health problem …
threat to the control of tuberculosis (TB) and constitutes an increasing public health problem …
Correlation between Genotypic and Phenotypic Testing for Resistance to Rifampin in Mycobacterium tuberculosis Clinical Isolates in Haiti: Investigation of Cases with …
O Ocheretina, VE Escuyer, MM Mabou, G Royal-Mardi… - PloS one, 2014 - journals.plos.org
The World Health Organization has recommended use of molecular-based tests
MTBDRplus and GeneXpert MTB/RIF to diagnose multidrug-resistant tuberculosis in …
MTBDRplus and GeneXpert MTB/RIF to diagnose multidrug-resistant tuberculosis in …
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