There has been recent renewed interest in studying human early embryonic development.
The advent of improved culture conditions to maintain blastocysts in vitro for an extended …

The basic body plan of the mammalian embryo is established through gastrulation, a pivotal
early postimplantation event during which the three major germ layers (endoderm …

Recent years have seen exciting progress across human embryo research, including new
methods for culturing embryos, transcriptional profiling of embryogenesis and gastrulation …

Establishing the different lineages of the early mammalian embryo takes place over several
days and several rounds of cell divisions from the fertilized egg. The resulting blastocyst …

Animals use diverse strategies to specify tissue lineages during development. A common
strategy is to partition maternally supplied and localized lineage determinants into …

Understanding human embryology has historically relied on comparative approaches using
mammalian model organisms. With the advent of low-input methods to investigate genetic …

The preimplantation period of mouse early embryonic development is devoted to the
specification of two extraembryonic tissues and their spatial segregation from the pluripotent …

During mammalian preimplantation development, the fertilised egg gives rise to a group of
pluripotent embryonic cells, the epiblast, and to the extraembryonic lineages that support the …

A critical point in mammalian development is when the early embryo implants into its
mother's uterus. This event has historically been difficult to study due to the fact that it occurs …

The cell biology of the early processes of mammalian embryogenesis, such as germ-layer
formation, has been technically challenging to study owing to the size and accessibility of …