Repeated amphetamine administration alters AMPA receptor subunit expression in rat nucleus accumbens and medial prefrontal cortex

W Lu, ME Wolf - Synapse, 1999 - Wiley Online Library
Glutamate is critical for the induction and maintenance of behavioral sensitization and
associated neuroadaptations in the mesocorticolimbic dopamine (DA) system. We have …

Repeated amphetamine administration alters the expression of mRNA for AMPA receptor subunits in rat nucleus accumbens and prefrontal cortex

W Lu, H Chen, CJ Xue, ME Wolf - Synapse, 1997 - Wiley Online Library
Recent evidence suggests that behavioral sensitization to amphetamine is associated with
alterations in excitatory amino acid (EAA) transmission in perikarya (ventral tegmental area) …

Repeated administration of amphetamine or cocaine does not alter AMPA receptor subunit expression in the rat midbrain

W Lu, LM Monteggia, ME Wolf - Neuropsychopharmacology, 2002 - Elsevier
We previously reported that ventral tegmental area (VTA) dopamine neurons are
supersensitive to AMPA when recorded three days after discontinuing repeated …

Amphetamine-induced plasticity of AMPA receptors in the ventral tegmental area: effects on extracellular levels of dopamine and glutamate in freely moving rats

M Giorgetti, G Hotsenpiller, P Ward… - Journal of …, 2001 - Soc Neuroscience
Previous electrophysiological studies suggested that the initiation of behavioral sensitization
to cocaine and amphetamine involves a transient increase in AMPA receptor …

Behavioral sensitization to amphetamine is not accompanied by changes in glutamate receptor surface expression in the rat nucleus accumbens

CL Nelson, M Milovanovic, JB Wetter… - Journal of …, 2009 - Wiley Online Library
We examined whether behavioral sensitization to amphetamine is associated with
redistribution of glutamate receptors (GluR) in the rat nucleus accumbens (NAc) or …

Increased responsiveness of ventral tegmental area dopamine neurons to glutamate after repeated administration of cocaine or amphetamine is transient and …

XF Zhang, XT Hu, FJ White, ME Wolf - Journal of Pharmacology and …, 1997 - ASPET
It is well established that behavioral sensitization to psychomotor stimulants is associated
with adaptations in the mesoaccumbens dopamine (DA) system. We showed previously that …

Differentially altered mGluR1 and mGluR5 mRNA expression in rat caudate nucleus and nucleus accumbens in the development and expression of behavioral …

L Mao, JQ Wang - Synapse, 2001 - Wiley Online Library
Altered glutamatergic transmission in the striatum may be implicated in behavioral
sensitization to repeated amphetamine (AMPH) administration. Quantitative in situ …

Behavioral sensitization to cocaine is associated with increased AMPA receptor surface expression in the nucleus accumbens

AC Boudreau, ME Wolf - Journal of Neuroscience, 2005 - Soc Neuroscience
Regulation of AMPA receptor trafficking is important for many forms of neuronal plasticity. In
this study, a protein cross-linking assay was used to evaluate the contribution of AMPA …

Cell surface AMPA receptors in the rat nucleus accumbens increase during cocaine withdrawal but internalize after cocaine challenge in association with altered …

AC Boudreau, JM Reimers, M Milovanovic… - Journal of …, 2007 - Soc Neuroscience
Although some studies report increased responsiveness of nucleus accumbens (NAc)
AMPA receptors (AMPARs) after withdrawal from repeated cocaine treatment, others report …

Repeated exposure to morphine alters surface expression of AMPA receptors in the rat medial prefrontal cortex

AL Mickiewicz, TC Napier - European Journal of Neuroscience, 2011 - Wiley Online Library
Behavioral sensitization describes the intensification of motor activity that results from
repeated exposure to drugs of misuse, and the underlying neuronal adaptations are …