Mesenchymal stem cells in treatment of spinal cord injury and amyotrophic lateral sclerosis

E Sykova, D Cizkova, S Kubinova - Frontiers in cell and …, 2021 - frontiersin.org
Preclinical and clinical studies with various stem cells, their secretomes, and extracellular
vesicles (EVs) indicate their use as a promising strategy for the treatment of various …

The role of mesenchymal stromal cells in spinal cord injury, regenerative medicine and possible clinical applications

S Forostyak, P Jendelova, E Sykova - Biochimie, 2013 - Elsevier
Diseases of the central nervous system still remain among the most challenging pathologies
known to mankind, having no or limited therapeutic possibilities and a very pessimistic …

Mesenchymal stem cells in the treatment of spinal cord injury: Mechanisms, current advances and future challenges

Y Xia, J Zhu, R Yang, H Wang, Y Li, C Fu - Frontiers in Immunology, 2023 - frontiersin.org
Spinal cord injury (SCI) has considerable impact on patient physical, mental, and financial
health. Secondary SCI is associated with inflammation, vascular destruction, and …

Mesenchymal stem cells and the neuronal microenvironment in the area of spinal cord injury

YO Mukhamedshina, OA Gracheva… - Neural regeneration …, 2019 - journals.lww.com
Cell-based technologies are used as a therapeutic strategy in spinal cord injury (SCI).
Mesenchymal stem cells (MSCs), which secrete various neurotrophic factors and cytokines …

Sources and therapeutic strategies of mesenchymal stem cells in regenerative medicine

M Kamal, D Kassem, KH Haider - Handbook of stem cell therapy, 2022 - Springer
During the past decade, mesenchymal stem cells (MSCs) have made their mark as a
potential weapon in regenerative medicine. Since their first isolation by Friedenstein in the …

[HTML][HTML] Differentiation of human mesenchymal stem cells towards neuronal lineage: clinical trials in nervous system disorders

R Hernández, C Jiménez-Luna… - Biomolecules & …, 2020 - ncbi.nlm.nih.gov
Mesenchymal stem cells (MSCs) have been proposed as an alternative therapy to be
applied into several pathologies of the nervous system. These cells can be obtained from …

The combined strategy of mesenchymal stem cells and tissue-engineered scaffolds for spinal cord injury regeneration

P Bramanti, E Mazzon - … and Therapeutic Medicine, 2017 - spandidos-publications.com
Spinal cord injury (SCI) is a traumatic lesion that can result in the loss of motor or sensory
neurons. Stem cell (SC)‑based therapies have been demonstrated to promote neuronal …

Roles of mesenchymal stem cells in spinal cord injury

J Qu, H Zhang - Stem cells international, 2017 - Wiley Online Library
Spinal cord injury (SCI) represents one of the most complicated and heterogeneous
pathological processes of central nervous system (CNS) impairments, which is still beyond …

Mesenchymal stem cells: potential in treatment of neurodegenerative diseases

T Tanna, V Sachan - Current stem cell research & therapy, 2014 - ingentaconnect.com
Mesenchymal Stem Cells or Marrow Stromal Cells (MSCs) have long been viewed as a
potent tool for regenerative cell therapy. MSCs are easily accessible from both healthy donor …

Mesenchymal stem cells for spinal cord injury: current options, limitations, and future of cell therapy

F Cofano, M Boido, M Monticelli, F Zenga… - International journal of …, 2019 - mdpi.com
Spinal cord injury (SCI) constitutes an inestimable public health issue. The most crucial
phase in the pathophysiological process of SCI concerns the well-known secondary injury …