Chemokines play a critical role in cell migration and activation through binding to G-protein
coupled cell-surface receptors with seven transmembrane domains. Chemokines are …

Chemokines are a class of small heparin-binding molecules which orchestrate the infiltration
of leukocyte subsets into the liver during acute and chronic injury. In experimental models of …

Liver fibrosis is the common sequel of chronic liver diseases and is associated with high
morbidity and mortality in affected patients. In recent years, the contribution of chemokines …

[Frontiers in Bioscience 7, d1899-1914, September 1, 2002] 1899 CHEMOKINES IN LIVER
INFLAMMATION AND FIBROSIS Fabio Marra Dipart Page 1 [Frontiers in Bioscience 7 …

Chemokines are a class of small chemotactic molecules with cytokine-like functions, which
are well known to orchestrate inflammatory responses within different organs. Overall, more …

Hepatic fibrosis develops as a response to chronic liver injury and almost exclusively occurs
in a proinflammatory environment. However, the role of inflammatory mediators in fibrogenic …

Chemokines are a class of small cytokine-like molecules that orchestrate immune cell
infiltration into the liver in response to acute and chronic injuries. Apart from their …

Methods: A comprehensive literature review was performed searching PubMed for relevant
English studies and texts regarding chemokine biology, chronic liver disease and liver …

Hepatic fibrosis is the result of a complex interplay between resident hepatic cells, infiltrating
inflammatory cells, and a number of locally-acting peptides called cytokines [1]. Cytokines …

Despite increasing knowledge about molecular pathways in pathogenesis of chronic liver
disease, selective therapeutic options are scarce, especially in advanced diseases …