Background Neuroinflammation is thought to contribute to psychiatric and neurological
disorders such as major depression and Alzheimer's disease (AD). N-6 polyunsaturated fatty …

Neuroinflammation is present in the majority of acute and chronic neurological disorders.
Excess or prolonged inflammation in the brain is thought to exacerbate neuronal damage …

Background Neuroinflammation is a proposed mechanism by which Alzheimer's disease
(AD) pathology potentiates neuronal death and cognitive decline. Consumption of omega-3 …

Abstract Purpose Interleukin (IL)-1β can activate glial cells to trigger neuroinflammation and
neurodegeneration. Lower omega (n)-3 polyunsaturated fatty acids (PUFAs) and lower n-3/n …

Polyunsaturated fatty acids (PUFAs) display immunomodulatory properties in the brain, n-3
PUFAs being able to reduce inflammation whereas n-6 PUFAs are more pro-inflammatory. It …

Dietary n-3 polyunsaturated fatty acids (PUFAs) are critical components of inflammatory
response and memory impairment. However, the mechanisms underlying the sensitizing …

Background Neuroinflammation is a recognized hallmark of Alzheimer's disease, along with
accumulation of amyloid-β plaques, neurofibrillary tangles and synaptic loss. n-3 …

Classically, polyunsaturated fatty acids (PUFA) were largely thought to be relatively inert
structural components of brain, largely important for the formation of cellular membranes …

Alzheimer's disease (AD) is a neurodegenerative disorder without a known cure or effective
treatment. Research has identified several modifiable risk factors and suggested …

Neuroinflammation is believed to play an important role in neurological diseases such as
Alzheimer's disease (AD). Growing evidence suggests that n-3 PUFA have protective effects …