Leptin is a protein hormone that acts within the hypothalamus to suppress food intake and
decrease body adiposity, but it is increasingly clear that the hypothalamus is not the only site …

Receptors of leptin, the prototypical adipokine, are expressed throughout the cortex and
several other areas of the brain. Although typically studied for its role in energy intake and …

Leptin, a hormone produced by adipocytes, provides signals to specific regions of the
hypothalamus to control energy homeostasis. However, the past decade of research has not …

It is well documented that the hormone leptin signals information regarding the status of fat
stores to hypothalamic nuclei, which in turn control feeding behaviour and body weight …

The discovery of leptin was a major breakthrough in our understanding of the role of adipose
tissue as a storage and secretory organ. Leptin was initially thought to act mainly to prevent …

It is well established that the adipocyte-derived hormone leptin is an important circulating
satiety factor that regulates body weight and food intake via its actions on specific …

The adipocyte-derived hormone leptin is an important regulator of body weight and
metabolism through activation of brain leptin receptors expressed in regions such as the …

Cloned in 1994, the ob gene encodes the protein hormone leptin, which is produced and
secreted by white adipose tissue. Since its discovery, leptin has been found to have …

The discovery of leptin has enhanced understanding of the interrelationship between
adipose energy stores and neuronal circuits in the brain involved in energy balance and …

Leptin, a peptide hormone, is implicated in the modulation of food intake and maintenance
of energy balance in many vertebrates including humans. It is considered to act via its …