The bacterial superantigen and superantigen‐like proteins
The bacterial superantigens are protein toxins that bind to major histocompatibility complex
class II and T‐cell receptor to stimulate large numbers of T cells. The majority are produced …
class II and T‐cell receptor to stimulate large numbers of T cells. The majority are produced …
Gram‐positive bacterial superantigen outside‐in signaling causes toxic shock syndrome
AJ Brosnahan, PM Schlievert - The FEBS journal, 2011 - Wiley Online Library
Staphylococcus aureus and Streptococcus pyogenes (group A streptococci) are Gram‐
positive pathogens capable of producing a variety of bacterial exotoxins known as …
positive pathogens capable of producing a variety of bacterial exotoxins known as …
Superantigens: structure-function relationships
MD Baker, KR Acharya - International journal of medical microbiology, 2004 - Elsevier
Superantigens are a class of highly potent immuno-stimulatory molecules produced by
Staphylococcus aureus and Streptococcus pyogenes. These toxins possess the unique …
Staphylococcus aureus and Streptococcus pyogenes. These toxins possess the unique …
[HTML][HTML] Streptococcal superantigens: biological properties and potential role in disease
Superantigens (SAgs) are a family of highly potent mitogens that share the ability to trigger
excessive stimulation of human and other mammalian T lymphocytes. This leads to a …
excessive stimulation of human and other mammalian T lymphocytes. This leads to a …
Toxic shock syndrome and bacterial superantigens: an update
JK McCormick, JM Yarwood… - Annual Reviews in …, 2001 - annualreviews.org
▪ Abstract Toxic shock syndrome (TSS) is an acute onset illness characterized by fever, rash
formation, and hypotension that can lead to multiple organ failure and lethal shock, as well …
formation, and hypotension that can lead to multiple organ failure and lethal shock, as well …
Staphylococcal and streptococcal superantigens: molecular, biological and clinical aspects
JE Alouf, H Müller-Alouf - International journal of medical microbiology, 2003 - Elsevier
Superantigens (SAgs) include a class of certain bacterial and viral proteins exhibiting highly
potent lymphocyte-transforming (mitogenic) activity towards human and or other mammalian …
potent lymphocyte-transforming (mitogenic) activity towards human and or other mammalian …
Superantigens–powerful modifiers of the immune system
Superantigens are powerful microbial toxins that activate the immune system by binding to
class II major histocompatibility complex and T-cell receptor molecules. They cause a …
class II major histocompatibility complex and T-cell receptor molecules. They cause a …
Manipulation of innate and adaptive immunity by staphylococcal superantigens
SW Tuffs, SMM Haeryfar, JK McCormick - Pathogens, 2018 - mdpi.com
Staphylococcal superantigens (SAgs) constitute a family of potent exotoxins secreted by
Staphylococcus aureus and other select staphylococcal species. SAgs function to cross-link …
Staphylococcus aureus and other select staphylococcal species. SAgs function to cross-link …
Development of engineered vaccines effective against structurally related bacterial superantigens
RG Ulrich, MA Olson, S Bavari - Vaccine, 1998 - Elsevier
Staphylococcal and streptococcal superantigens are exotoxins that may be linked to many
human pathologies involving impaired immune functions. Despite considerable sequence …
human pathologies involving impaired immune functions. Despite considerable sequence …
Staphylococcal superantigen-like protein 3 binds to the Toll-like receptor 2 extracellular domain and inhibits cytokine production induced by Staphylococcus aureus …
R Yokoyama, S Itoh, G Kamoshida, T Takii… - Infection and …, 2012 - Am Soc Microbiol
Staphylococcal superantigen-like proteins (SSLs) are a family of exoproteins sharing
structural similarity with superantigens, but no superantigenic activity. Corresponding host …
structural similarity with superantigens, but no superantigenic activity. Corresponding host …