Background Obesity increases the risk of several chronic diseases, but the extent to which
the obesity-related loss of disease-free years varies by lifestyle category and across …

Background Although overweight and obesity have been studied in relation to individual
cardiometabolic diseases, their association with risk of cardiometabolic multimorbidity is …

Background The accumulation of disparate diseases in complex multimorbidity makes
prevention difficult if each disease is targeted separately. We aimed to examine obesity as a …

Background Underweight and severe and morbid obesity are associated with highly
elevated risks of adverse health outcomes. We estimated trends in mean body-mass index …

Background Individuals with obesity do not represent a homogeneous group in terms of
cardiometabolic risk. Using 3 nationally representative British birth cohorts, we investigated …

Background Despite the increased risk of cardiovascular disease and type 2 diabetes
associated with excess bodyweight, development of a clinically meaningful metric for health …

Importance A healthy lifestyle is associated with a reduced risk of cardiovascular disease in
adults with obesity. Little is known about the associations between a healthy lifestyle and the …

Background Targeted obesity prevention policies would benefit from the identification of
population groups with the highest risk of weight gain. The relative importance of adult age …

Background Although the rising pandemic of obesity has received major attention in many
countries, the effects of this attention on trends and the disease burden of obesity remain …

National and international recommendations of healthy body mass index (BMI) are primarily
based on evidence in young and middle-aged populations, with an insufficient …