A human model of Buruli ulcer: The case for controlled human infection and considerations for selecting a Mycobacterium ulcerans challenge strain
S Muhi, J Osowicki, D O'Brien… - PLOS Neglected …, 2023 - journals.plos.org
Critical knowledge gaps regarding infection with Mycobacterium ulcerans, the cause of
Buruli ulcer (BU), have impeded development of new therapeutic approaches and vaccines …
Buruli ulcer (BU), have impeded development of new therapeutic approaches and vaccines …
Mycobacterium ulcerans challenge strain selection for a Buruli ulcer controlled human infection model
S Muhi, AH Buultjens, JL Porter… - PLOS Neglected …, 2024 - journals.plos.org
Critical scientific questions remain regarding infection with Mycobacterium ulcerans, the
organism responsible for the neglected tropical disease, Buruli ulcer (BU). A controlled …
organism responsible for the neglected tropical disease, Buruli ulcer (BU). A controlled …
Mycobacterium ulcerans Mouse Model Refinement for Pre-Clinical Profiling of Vaccine Candidates
A Bénard, C Sala, G Pluschke - PLoS One, 2016 - journals.plos.org
Buruli Ulcer is a neglected tropical disease leading to extensive disabilities and morbidity in
West Africa. In this paper we sought to characterize various strains of Mycobacterium …
West Africa. In this paper we sought to characterize various strains of Mycobacterium …
Understanding the transmission of Mycobacterium ulcerans: A step towards controlling Buruli ulcer
Mycobacterium ulcerans is the causative agent of Buruli ulcer, a rare but chronic debilitating
skin and soft tissue disease found predominantly in West Africa and Southeast Australia …
skin and soft tissue disease found predominantly in West Africa and Southeast Australia …
Buruli ulcer: The Efficacy of Innate Immune Defense May Be a Key Determinant for the Outcome of Infection With Mycobacterium ulcerans
K Röltgen, G Pluschke - Frontiers in microbiology, 2020 - frontiersin.org
Buruli ulcer (BU) is a neglected, tropical infectious disease of the skin and the subcutaneous
tissue caused by Mycobacterium ulcerans. This pathogen has emerged as a new species …
tissue caused by Mycobacterium ulcerans. This pathogen has emerged as a new species …
[PDF][PDF] The immunology of Buruli ulcer
J Fevereiro, AG Fraga, J Pedrosa - Buruli Ulcer: Mycobacterium …, 2019 - library.oapen.org
Buruli ulcer (BU) represents a unique human mycobacteriosis. Caused by Mycobacterium
ulcerans, the disease spectrum is dominated by the activity of mycolactone, a dermanecrotic …
ulcerans, the disease spectrum is dominated by the activity of mycolactone, a dermanecrotic …
Local Cellular Immune Responses and Pathogenesis of Buruli Ulcer Lesions in the Experimental Mycobacterium Ulcerans Pig Infection Model
M Bolz, N Ruggli, N Borel, G Pluschke… - PLoS neglected tropical …, 2016 - journals.plos.org
Background Buruli ulcer is a neglected tropical disease of the skin that is caused by infection
with Mycobacterium ulcerans. We recently established an experimental pig (Sus scrofa) …
with Mycobacterium ulcerans. We recently established an experimental pig (Sus scrofa) …
Spontaneous Healing of Mycobacterium ulcerans Lesions in the Guinea Pig Model
R Silva-Gomes, E Marcq, G Trigo… - PLoS neglected …, 2015 - journals.plos.org
Buruli Ulcer (BU) is a necrotizing skin disease caused by Mycobacterium ulcerans infection.
BU is characterized by a wide range of clinical forms, including non-ulcerative cutaneous …
BU is characterized by a wide range of clinical forms, including non-ulcerative cutaneous …
Linking the Mycobacterium ulcerans environment to Buruli ulcer disease: Progress and challenges
Buruli ulcer (BU), the second most common mycobacterial disease in West Africa, is a
necrotizing skin disease that can lead to high morbidity in affected patients. The disease is …
necrotizing skin disease that can lead to high morbidity in affected patients. The disease is …
Recombinant BCG Expressing Mycobacterium ulcerans Ag85A Imparts Enhanced Protection against Experimental Buruli ulcer
BE Hart, LP Hale, S Lee - PLoS neglected tropical diseases, 2015 - journals.plos.org
Buruli ulcer, an emerging tropical disease caused by Mycobacterium ulcerans (MU), is
characterized by disfiguring skin necrosis and high morbidity. Relatively little is understood …
characterized by disfiguring skin necrosis and high morbidity. Relatively little is understood …