[HTML][HTML] Asprosin exerts pro-inflammatory effects in THP-1 macrophages mediated via the toll-like receptor 4 (TLR4) pathway
K Shabir, S Gharanei, S Orton, V Patel… - International Journal of …, 2022 - mdpi.com
Adipose tissue is a dynamic endocrine organ, secreting a plethora of adipokines which play
a key role in regulating metabolic homeostasis and other physiological processes. An …
a key role in regulating metabolic homeostasis and other physiological processes. An …
[HTML][HTML] Asprosin enhances cytokine production by a co-culture of fully differentiated mature adipocytes and macrophages leading to the exacerbation of the condition …
AI Mazur-Bialy - International Journal of Molecular Sciences, 2023 - mdpi.com
Asprosin, a fasting-induced, glucogenic, and orexigenic adipokine, has gained popularity in
recent years as a potential target in the fight against obesity and its complications. However …
recent years as a potential target in the fight against obesity and its complications. However …
Asprosin attenuates insulin signaling pathway through PKCδ‐activated ER stress and inflammation in skeletal muscle
TW Jung, HC Kim, HU Kim, T Park… - Journal of cellular …, 2019 - Wiley Online Library
It has been reported that asprosin is a novel adipokine which is augmented in mice and
humans with type 2 diabetes (T2DM). Asprosin stimulates hepatic gluconeogenesis under …
humans with type 2 diabetes (T2DM). Asprosin stimulates hepatic gluconeogenesis under …
Asprosin impairs insulin secretion in response to glucose and viability through TLR4/JNK-mediated inflammation
T Lee, S Yun, JH Jeong, TW Jung - Molecular and cellular endocrinology, 2019 - Elsevier
Severe inflammation in the islets is observed in obese patients with type 2 diabetes.
Inflammation in the islets is caused by obesity-induced serum free fatty acids. Asprosin is a …
Inflammation in the islets is caused by obesity-induced serum free fatty acids. Asprosin is a …
Asprosin, a novel pleiotropic adipokine implicated in fasting and obesity-related cardio-metabolic disease: Comprehensive review of preclinical and clinical evidence
White adipose tissue is a dynamic endocrine organ that releases an array of adipokines,
which play a key role in regulating metabolic homeostasis and multiple other physiological …
which play a key role in regulating metabolic homeostasis and multiple other physiological …
Can the new adipokine asprosin be a metabolic troublemaker for cardiovascular diseases? A state-of-the-art review
Z Zhang, L Zhu, Z Wang, N Hua, S Hu… - Progress in Lipid Research, 2023 - Elsevier
Adipokines play a significant role in cardiometabolic diseases. Asprosin, a newly discovered
adipokine, was first identified as a glucose-raising protein hormone. Asprosin also …
adipokine, was first identified as a glucose-raising protein hormone. Asprosin also …
[HTML][HTML] Novel adipokine asprosin modulates browning and adipogenesis in white adipose tissue
Y Miao, H Qin, Y Zhong, K Huang… - Journal of …, 2021 - joe.bioscientifica.com
Obesity is an increasingly serious epidemic worldwide characterized by an increase in the
number and size of adipocytes. Adipose tissue maintains the balance between lipid storage …
number and size of adipocytes. Adipose tissue maintains the balance between lipid storage …
Circulating asprosin concentrations are increased in type 2 diabetes mellitus and independently associated with fasting glucose and triglyceride
L Zhang, C Chen, N Zhou, Y Fu, X Cheng - Clinica chimica acta, 2019 - Elsevier
Background Asprosin has been identified as a novel hormone enriched in white adipose
tissue and is pathologically increased in insulin-resistant mice and humans. However …
tissue and is pathologically increased in insulin-resistant mice and humans. However …
Circulating levels of asprosin and its association with insulin resistance and renal function in patients with type 2 diabetes mellitus and diabetic nephropathy
Introduction Adipokines play an important role in the development of type 2 diabetes mellitus
(T2DM) and its complications like nephropathy. Asprosin is a newly discovered adipokine …
(T2DM) and its complications like nephropathy. Asprosin is a newly discovered adipokine …
[HTML][HTML] Asprosin in the paraventricular nucleus induces sympathetic activation and pressor responses via cAMP-dependent ROS production
XL Wang, JX Wang, JL Chen, WY Hao, WZ Xu… - International journal of …, 2022 - mdpi.com
Asprosin is a newly discovered adipokine that is involved in regulating metabolism.
Sympathetic overactivity contributes to the pathogenesis of several cardiovascular diseases …
Sympathetic overactivity contributes to the pathogenesis of several cardiovascular diseases …