Methodological challenges in utilizing mi RNA s as circulating biomarkers
L Moldovan, KE Batte, J Trgovcich… - Journal of cellular …, 2014 - Wiley Online Library
Micro RNA s (mi RNA s) have emerged as important regulators in the post‐transcriptional
control of gene expression. The discovery of their presence not only in tissues but also in …
control of gene expression. The discovery of their presence not only in tissues but also in …
The biology of circulating micro RNA s in cardiovascular disease
PK Min, SY Chan - European journal of clinical investigation, 2015 - Wiley Online Library
Background Since their first description in mammalian cells, more than 2500 micro RNA
molecules have been predicted or verified within human cells. Recently, extracellular micro …
molecules have been predicted or verified within human cells. Recently, extracellular micro …
Circulating microRNAs: novel biomarkers for cardiovascular diseases
J Xu, J Zhao, G Evan, C Xiao, Y Cheng… - Journal of molecular …, 2012 - Springer
MicroRNAs (miRNAs) are a novel class of small, non-coding, single-stranded RNAs that
negatively regulate gene expression via translational inhibition or mRNA degradation …
negatively regulate gene expression via translational inhibition or mRNA degradation …
Standardizing analysis of circulating microRNA: clinical and biological relevance
Circulating microRNAs (c‐miRNAs) provide a new dimension as clinical biomarkers for
disease diagnosis, progression, and response to treatment. However, the discovery of …
disease diagnosis, progression, and response to treatment. However, the discovery of …
Circulating microRNAs: Biomarkers of disease
Y Wu, Q Li, R Zhang, X Dai, W Chen, D Xing - Clinica Chimica Acta, 2021 - Elsevier
MicroRNAs are a class of endogenous noncoding single-stranded RNA molecules with
approximately 20–24 nucleotides and are associated with a broad range of biological …
approximately 20–24 nucleotides and are associated with a broad range of biological …
Circulating microRNAs: Association with disease and potential use as biomarkers
The control of gene expression by microRNAs influences many cellular processes and has
been implicated in the control of many (patho) physiological states. Recently, microRNAs …
been implicated in the control of many (patho) physiological states. Recently, microRNAs …
Cell‐free microRNAs in blood and other body fluids, as cancer biomarkers
B Ortiz‐Quintero - Cell proliferation, 2016 - Wiley Online Library
The discovery of cell‐free micro RNA s (mi RNA s) in serum, plasma and other body fluids
has yielded an invaluable potential source of non‐invasive biomarkers for cancer and other …
has yielded an invaluable potential source of non‐invasive biomarkers for cancer and other …
[HTML][HTML] Issues and prospects of microRNA-based biomarkers in blood and other body fluids
Cell-free circulating microRNAs (miRNAs) in the blood are good diagnostic biomarker
candidates for various physiopathological conditions, including cancer, neurodegeneration …
candidates for various physiopathological conditions, including cancer, neurodegeneration …
Circulating miRNAs: reflecting or affecting cardiovascular disease?
VPM van Empel, LJ De Windt, PAC Martins - Current hypertension reports, 2012 - Springer
MicroRNAs are a class of small, noncoding RNAs encoded by the metazoan genome that
regulate protein expression. A collection of studies point to vital roles for microRNAs in the …
regulate protein expression. A collection of studies point to vital roles for microRNAs in the …
[HTML][HTML] Serum microRNAs are promising novel biomarkers
S Gilad, E Meiri, Y Yogev, S Benjamin, D Lebanony… - PloS one, 2008 - journals.plos.org
Background Circulating nucleic acids (CNAs) offer unique opportunities for early diagnosis
of clinical conditions. Here we show that microRNAs, a family of small non-coding regulatory …
of clinical conditions. Here we show that microRNAs, a family of small non-coding regulatory …