[HTML][HTML] Nanoparticles induce dermal and intestinal innate immune system responses in zebrafish embryos

NR Brun, BEV Koch, M Varela… - Environmental …, 2018 - pubs.rsc.org
Major molecular mechanisms that underpin the toxicity of nanoparticles (NPs) are the
formation of reactive oxygen species and the induction of inflammation. The latter is …

[PDF][PDF] Zebrafish (Danio rerio) as an ecotoxicological model for Nanomaterial induced toxicity profiling

YK Mishra, SK Verma, A Nandi… - Precision …, 2021 - portal.findresearcher.sdu.dk
With the advancement of technologies, the evolution of nanoscience is occurring at a rapid
pace. The demand for nanomaterials in various industries has increased. However, they …

Zebrafish models for the safety and therapeutic testing of nanoparticles with a focus on macrophages

A Pensado-López, J Fernández-Rey, P Reimunde… - Nanomaterials, 2021 - mdpi.com
New nanoparticles and biomaterials are increasingly being used in biomedical research for
drug delivery, diagnostic applications, or vaccines, and they are also present in numerous …

Immunotoxicology of non-functionalized engineered nanoparticles in aquatic organisms with special emphasis on fish—Review of current knowledge, gap …

B Jovanović, D Palić - Aquatic toxicology, 2012 - Elsevier
The rapid increase in use of nanotechnology products is increasing the presence of metal,
metal-oxide and carbon-based nanoparticles in the aquatic environment. These non …

Adoption of in vitro systems and zebrafish embryos as alternative models for reducing rodent use in assessments of immunological and oxidative stress responses to …

HJ Johnston, R Verdon, S Gillies… - Critical Reviews in …, 2018 - Taylor & Francis
Assessing the safety of engineered nanomaterials (NMs) is paramount to the responsible
and sustainable development of nanotechnology, which provides huge societal benefits …

[HTML][HTML] Immunotoxicity responses to polystyrene nanoplastics and their related mechanisms in the liver of zebrafish (Danio rerio) larvae

H Cheng, Z Duan, Y Wu, Y Wang, H Zhang, Y Shi… - Environment …, 2022 - Elsevier
Nanoplastics in aquatic environments may induce adverse immunotoxicity effects in fish.
However, there is insufficient evidence on the visible immunotoxicity endpoints in the larval …

Immunomodulation by Different Types of N-Oxides in the Hemocytes of the Marine Bivalve Mytilus galloprovincialis

C Ciacci, B Canonico, D Bilaniĉovă, R Fabbri… - PLoS …, 2012 - journals.plos.org
The potential toxicity of engineered nanoparticles (NPs) for humans and the environment
represents an emerging issue. Since the aquatic environment represents the ultimate sink …

The invertebrate immune system as a model for investigating the environmental impact of nanoparticles

L Canesi, P Procházková - Nanoparticles and the immune system, 2014 - Elsevier
Invertebrates lack an adaptive immunity; however, they are endowed with a potent and
complex innate immune system similar to that of vertebrates. In most invertebrates, free …

Immunotoxicity of four nanoparticles to a marine bivalve species, Tegillarca granosa

S Zha, J Rong, X Guan, Y Tang, Y Han, G Liu - Journal of hazardous …, 2019 - Elsevier
The increasing application of nanomaterials drives the unintentional release of
nanoparticles (NPs) into the ocean, which may pose a potential threat to marine organisms …

Zebrafish as a model to evaluate nanoparticle toxicity

E Haque, AC Ward - Nanomaterials, 2018 - mdpi.com
Nanoparticles are increasingly being developed for in vivo use, from targeted drug delivery
to diagnostics, where they have enormous potential, while they are also being used for a …