The free-radical gas nitric oxide (NO) plays an important role in a diverse range of
physiological processes. It is synthesized from the precursor l-arginine by the enzyme NO …

Evidence has been reported supporting the hypothesis that nitric oxide (NO) partially
mediates the expression of morphine dependence. To examine whether NO‐related agents …

Nitric oxide synthesis contributes to opiate tolerance and dependence. Nicotine
dependence and abstinence syndrome in the rat appear to involve opiate mechanisms …

The catastrophic effects of opioids use on public health and the economy are documented
clearly in numerous studies. Repeated morphine administration can lead to either a …

The purpose of this study is to describe the interrelationship between nitric oxide (NO) and
nicotine in cigarette smoking addiction, in view of the underlying hypothesis that NO …

The freely diffusible gaseous compound nitric oxide (NO) has recently been discovered to
be an important cellular messenger in many organ systems throughout the body. The …

Behavioral sensitization to cocaine was tested for in rats pretreated with a nitric oxide (NO)
synthase inhibitor, Nω-nitro-l-arginine methyl ester (L-NAME) or 7-nitro indazole (7-NI). A 5 …

Several amphetamine analogs are potent psychostimulants and major drugs of abuse. In
animal models, the psychomotor and reinforcing effects of amphetamine, methamphetamine …

To examine whether nitric oxide (NO) affects alcohol (ethanol) narcosis, adult male rats were
pretreated with a NO synthase (NOS) inhibitor, NG‐nitro‐i‐arginine methyl ester (NAME); a …

The effect of the nitric oxide (NO) synthase inhibitor lN G-nitroarginine methyl ester (l-NAME,
5–20 mg/kg ip) and N G-nitro-l-arginine (NO 2 Arg, 5–20 mg/kg ip) on morphine-induced …