[HTML][HTML] Molecular and nanoparticulate agents for photodynamic therapy guided by near infrared imaging

A Grebinyk, O Chepurna, M Frohme, J Qu… - … of Photochemistry and …, 2024 - Elsevier
Photodynamic therapy (PDT) of cancer is a clinically approved, minimally invasive
therapeutic approach, combining PDT drug (photosensitizer, PS), molecular oxygen and …

Nanoparticle-based photodynamic therapy: current status and future application to improve outcomes of cancer treatment

K Ogawara, K Higaki - Chemical and Pharmaceutical Bulletin, 2017 - jstage.jst.go.jp
Photodynamic therapy (PDT) is an emerging cancer treatment that uses photosensitizers
(PS), along with light to activate them, resulting in oxidation of various biological …

Photodynamic nanomedicine in the treatment of solid tumors: perspectives and challenges

A Master, M Livingston, AS Gupta - Journal of controlled release, 2013 - Elsevier
Photodynamic therapy (PDT) is a promising treatment strategy where activation of
photosensitizer drugs with specific wavelengths of light results in energy transfer cascades …

Bioactivatable reactive oxygen species-sensitive nanoparticulate system for chemo-photodynamic therapy

Y Kim, S Uthaman, S Pillarisetti, K Noh, KM Huh… - Acta Biomaterialia, 2020 - Elsevier
Bioactivatable polymer nanoparticles (NPs) have attracted considerable attention as a
prospective cancer therapy. Herein, we describe bioactivatable reactive oxygen species …

[HTML][HTML] Ultra-small pyropheophorbide-a nanodots for near-infrared fluorescence/photoacoustic imaging-guided photodynamic therapy

K Siwawannapong, R Zhang, H Lei, Q Jin, W Tang… - Theranostics, 2020 - ncbi.nlm.nih.gov
Abstract Rationale: Nanoparticles (NPs) that are rapidly eliminated from the body offer great
potential in clinical test. Renal excretion of small particles is preferable over other clearance …

Chemophototherapy: an emerging treatment option for solid tumors

D Luo, KA Carter, D Miranda, JF Lovell - Advanced Science, 2017 - Wiley Online Library
Near infrared (NIR) light penetrates human tissues with limited depth, thereby providing a
method to safely deliver non‐ionizing radiation to well‐defined target tissue volumes. Light …

Light-triggered photodynamic nanomedicines for overcoming localized therapeutic efficacy in cancer treatment

J Choi, IC Sun, HS Hwang, HY Yoon, K Kim - Advanced Drug Delivery …, 2022 - Elsevier
Photodynamic nanomedicines have significantly enhanced the therapeutic efficacy of
photosensitizers (PSs) by overcoming critical limitations of PSs such as poor water solubility …

[HTML][HTML] Core–shell polymeric nanoparticles co-loaded with photosensitizer and organic dye for photodynamic therapy guided by fluorescence imaging in near and …

OM Chepurna, A Yakovliev, R Ziniuk… - Journal of …, 2020 - Springer
Background Biodistribution of photosensitizer (PS) in photodynamic therapy (PDT) can be
assessed by fluorescence imaging that visualizes the accumulation of PS in malignant …

[HTML][HTML] Current limitations and recent progress in nanomedicine for clinically available photodynamic therapy

J Park, YK Lee, IK Park, SR Hwang - Biomedicines, 2021 - mdpi.com
Photodynamic therapy (PDT) using oxygen, light, and photosensitizers has been receiving
great attention, because it has potential for making up for the weakness of the existing …

A nano approach to formulate photosensitizers for photodynamic therapy

P Pallavi, P Sharmiladevi, V Haribabu… - Current …, 2022 - ingentaconnect.com
Conventional treatment modalities for tumors face a variety of pitfalls, including nonspecific
interactions leading to multiple adverse effects. These adverse effects are being overcome …