Colorectal cancer (CRC) is the third most common malignant tumor and one of the deadliest
cancers. At molecular level, CRC is a heterogeneous disease that could be divided in four …

Tumor sidedness has emerged as an important prognostic and predictive factor in the
treatment of colorectal cancer. Recent studies demonstrate that patients with advanced right …

Introduction: Colorectal cancer is one of the most common malignancies in the world, and it
exhibits differences in incidence, pathogenesis, molecular pathways, and outcome …

Colorectal cancer (CRC) exhibits differences in incidence, pathogenesis, molecular
pathways and outcome depending on the location of the tumor. This review focuses on the …

Background. Several prognostic factors have been used to guide therapy for colon cancer
(CC). However, the relationship between CC laterality (sidedness) and prognosis remains …

In the current era of precision oncology, it is widely acknowledged that CRC is a
heterogeneous disease entity. Tumor location (right-or left-sided colon cancer or rectal …

For many years, developmental and physiological differences have been known to exist
between anatomic segments of the colorectum. Because of different outcomes, prognoses …

Simple Summary The versatile crosstalk between cancer cells and cancer-associated
fibroblasts (CAFs) of the tumour microenvironment (TME) drives colorectal carcinogenesis …

Background: Our study investigated the demographic characteristics of Mayo Clinic Colon
and Rectal Cancer Registry patients and sought to associate tumor location with overall …

Colon cancer is the third most commonly diagnosed cancer in the United States. Recent
reports have shown that the location of the primary tumor is of clinical importance. Patients …