Protective effect of heat-processed Gynostemma pentaphyllum on high fat diet-induced glucose metabolic disorders mice

JB Xie, P Xie, M Guo, FF Li, MY Xiao, YS Qi… - Frontiers in …, 2023 - frontiersin.org
Glucose metabolic disorders (GMD) can promote insulin resistance (IR) and diabetes, and
damage liver and kidney. Gynostemma pentaphyllum is commonly used in the clinical …

Liver lipidomics analysis reveals the anti-obesity and lipid-lowering effects of gypnosides from heat-processed Gynostemma pentaphyllum in high-fat diet fed mice

P Xie, JB Xie, MY Xiao, M Guo, YS Qi, FF Li, XL Piao - Phytomedicine, 2023 - Elsevier
Abstract Background In traditional Chinese medicine, Gynostemma pentaphyllum (G.
pentaphyllum) is widely used to treat conditions associated with hyperlipidemia, and its …

Effects of heat-processed Gynostemma pentaphyllum on high-fat diet-fed mice of obesity and functional analysis on network pharmacology and molecular docking …

P Xie, M Guo, JB Xie, MY Xiao, YS Qi, Y Duan… - Journal of …, 2022 - Elsevier
Ethnopharmacological relevance Gynostemma pentaphyllum has been used as traditional
medicine for many diseases, including metabolic syndrome (Mets), aging, diabetes …

The Role of Gynostemma pentaphyllum in Regulating Hyperlipidemia

Y Li, Q Ouyang, X Li, RN Alolgal, Y Fan… - The American Journal …, 2023 - World Scientific
Developing effective and safe lipid-lowering drugs is highly urgent. This study aims to
investigate the effectiveness and underlying mechanisms of Gynostemma pentaphyllum …

[HTML][HTML] Gypenoside ameliorates insulin resistance and hyperglycemia via the AMPK-mediated signaling pathways in the liver of type 2 diabetes mellitus mice

M Song, D Tan, B Li, Y Wang, L Shi - Food Science and Human Wellness, 2022 - Elsevier
Gynostemma pentaphyllum, also called “Southern Ginseng” in China, is a traditional Asian
folk medicinal plant. Gypenosides (Gps) are the biologically active constituents of G …

The potential molecular mechanism underlying gypenoside amelioration of atherosclerosis in ApoE−/− mice: A multi-omics investigation

X Ju, Y Liu, Y Wang, G Sui, Y Ma, H Cao, Y Cao, J Wu… - Heliyon, 2024 - cell.com
Gypenosides (Gyp) are bioactive components of Gynostemma pentaphyllum that have a
variety of pharmacological properties. Extracts of G. pentaphyllum have been found to be …

Gypenosides ameliorate high-fat diet-induced nonalcoholic fatty liver disease in mice by regulating lipid metabolism

T Zhou, L Cao, Y Du, L Qin, Y Lu, Q Zhang, Y He… - PeerJ, 2023 - peerj.com
Gypenosides (GP), extracted from the traditional Chinese herb Gynostemma pentaphyllum
(Thunb.) Makino, have been used to treat metabolic disorders, including lipid metabolism …

Gynostemma pentaphyllum and Gypenoside-IV Ameliorate Metabolic Disorder and Gut Microbiota in Diet-Induced-Obese Mice

X Shu, R Chen, M Yang, J Xu, R Gao, Y Hu… - Plant Foods for Human …, 2022 - Springer
Gynostemma pentaphyllum (G. pentaphyllum) is a perennial liana herb of the Cucurbitaceae
family which has both nutraceutical and pharmacological functions. The objective of the …

Gynostemma Pentaphyllum Extract Ameliorates High-Fat Diet-Induced Obesity in C57BL/6N Mice by Upregulating SIRT1

HS Lee, SM Lim, JI Jung, SM Kim, JK Lee, YH Kim… - Nutrients, 2019 - mdpi.com
Gynostemma pentaphyllum is widely used in Asia as a herbal medicine to treat type 2
diabetes, dyslipidemia, and inflammation. Here, we investigated the anti-obesity effect and …

Multi‑omics‑based analysis of the regulatory mechanism of gypenosides on bile acids in hypercholesterolemic mice

C Feng, Y Yang, A Lu, D Tan… - Experimental and …, 2023 - spandidos-publications.com
Gynostemma pentaphyllum is a traditional medicine used by ethnic minorities in southwest
China and gypenosides are currently recognized as essential components of the …