COVID‐19‐related neuropathology and microglial activation in elderly with and without dementia

TE Poloni, V Medici, M Moretti, SD Visonà… - Brain …, 2021 - Wiley Online Library
The actual role of SARS‐CoV‐2 in brain damage remains controversial due to lack of
matched controls. We aim to highlight to what extent is neuropathology determined by SARS …

[HTML][HTML] Brain autopsies of critically ill COVID-19 patients demonstrate heterogeneous profile of acute vascular injury, inflammation and age-linked chronic brain …

S Agrawal, JM Farfel, K Arfanakis, L Al-Harthi… - Acta neuropathologica …, 2022 - Springer
Background This study examined neuropathological findings of patients who died following
hospitalization in an intensive care unit with SARS-CoV-2. Methods Data originate from 20 …

SARS‐CoV‐2 and the brain: A review of the current knowledge on neuropathology in COVID‐19

A Maiese, AC Manetti, C Bosetti, F Del Duca… - Brain …, 2021 - Wiley Online Library
Abstract SARS‐CoV‐2 (severe acute respiratory syndrome coronavirus 2), the new
coronavirus responsible for the pandemic disease in the last year, is able to affect the central …

[HTML][HTML] Correlates of critical illness-related encephalopathy predominate postmortem COVID-19 neuropathology

N Deigendesch, L Sironi, M Kutza, S Wischnewski… - Acta …, 2020 - Springer
Infections with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) primarily
lead to upper respiratory tract infection and its sequelae frequently dominate the clinical …

Neuropathological findings from COVID‐19 patients with neurological symptoms argue against a direct brain invasion of SARS‐CoV‐2: A critical systematic review

G Cosentino, M Todisco, N Hota… - European journal of …, 2021 - Wiley Online Library
Background and purpose Neuropathological studies can elucidate the mechanisms of
nervous system damage associated with SARS‐CoV‐2 infection. Despite literature on this …

[HTML][HTML] Neurological sequelae in patients with COVID-19: a histopathological perspective

F Fisicaro, M Di Napoli, A Liberto, M Fanella… - International Journal of …, 2021 - mdpi.com
Background: Neuroinvasive properties of SARS-CoV-2 have allowed the hypothesis of
several pathogenic mechanisms related to acute and chronic neurological sequelae …

[HTML][HTML] Cognitive and neuropsychiatric manifestations of COVID-19 and effects on elderly individuals with dementia

S Alonso-Lana, M Marquié, A Ruiz… - Frontiers in aging …, 2020 - frontiersin.org
The coronavirus disease 2019 (COVID-19) caused by the severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) has rapidly spread worldwide and has had …

[HTML][HTML] Immediate and long-term consequences of COVID-19 infections for the development of neurological disease

MT Heneka, D Golenbock, E Latz, D Morgan… - Alzheimer's research & …, 2020 - Springer
Increasing evidence suggests that infection with Sars-CoV-2 causes neurological deficits in
a substantial proportion of affected patients. While these symptoms arise acutely during the …

COVID-19 neuropathology at columbia university irving medical center/New York presbyterian hospital

KT Thakur, EH Miller, MD Glendinning, O Al-Dalahmah… - Brain, 2021 - academic.oup.com
Many patients with SARS-CoV-2 infection develop neurological signs and symptoms;
although, to date, little evidence exists that primary infection of the brain is a significant …

[HTML][HTML] Neuropathology of patients with COVID-19 in Germany: a post-mortem case series

J Matschke, M Lütgehetmann, C Hagel… - The Lancet …, 2020 - thelancet.com
Background Prominent clinical symptoms of COVID-19 include CNS manifestations.
However, it is unclear whether severe acute respiratory syndrome coronavirus 2 (SARS-CoV …