Several natural products, bearing an embedded hexahydro‐2, 6‐methano‐1‐benzazocine
framework (3, 4‐benzomorphan)–a heterocyclic regioisomer of the 6, 7‐benzomorphan …

2‐Azabicyclo [mn 0] alkane ring systems, the conceptual precursors towards the synthesis of
Strychnos and Stemona classes of alkaloids, were synthesized from tert‐butyl 2 …

The morphinan alkaloid (–)-thebaine is an industrially important chemical intermediate
deployed in the semi-synthesis of various opioid medicines. Here, a seven-step total …

The regioselectivity of the Friedel-Crafts-type cyclisation of a range of γ-aryl-β-benzoylamido
acids, bearing oxy substituents at the C (3)-and C (4)-positions of the γ-aryl ring, has been …

The 2H-1, 4-benzoxazin-3-(4H)-one (1) and 3, 4-dihydro-2H-1, 4-benzoxazine (2) scaffolds
have been studied intensively as important heterocyclic systems for building natural 1, 2 and …

A very straightforward route to 1-azabicyclo alkaloid scaffolds with several ring sizes is
reported. The final bicyclic structures were built through a synthetic scheme that involved (i) …

A great variety of functionalized 7, 8‐benzo‐anellated 9‐azabicyclo‐[3.3. 1] nonan‐3‐ones
were prepared by methyl or benzyl chloroformate‐mediated condensation of isoquinolines …

Conclusions A number of alkaloids possessing the pyrrolo [2, 1-a] benzazepine unit are
widespread in nature. In particular, those alkaloids, eg, cephalotaxine, deoxyharringtonine …

The octahydroisoquinoline core of morphinan was assembled starting from readily available
arylcyclohexadienes. Three different approaches were developed, including a metal-and an …

Diversity-oriented synthesis of bicyclic and tricyclic alkaloids - Chemical Communications (RSC
Publishing) DOI:10.1039/B917965H Royal Society of Chemistry View PDF VersionPrevious …