[HTML][HTML] Cell size distribution of lineage data: analytic results and parameter inference
Recent advances in single-cell technologies have enabled time-resolved measurements of
the cell size over several cell cycles. These data encode information on how cells correct …
the cell size over several cell cycles. These data encode information on how cells correct …
Analytical cell size distribution: lineage-population bias and parameter inference
A Genthon - Journal of the Royal Society Interface, 2022 - royalsocietypublishing.org
We derive analytical steady-state cell size distributions for size-controlled cells in single-
lineage experiments, such as the mother machine, which are fundamentally different from …
lineage experiments, such as the mother machine, which are fundamentally different from …
[HTML][HTML] Analysis of cell size homeostasis at the single-cell and population level
P Thomas - Frontiers in Physics, 2018 - frontiersin.org
Growth pervades all areas of life from single cells to cell populations to tissues. Cell size
often fluctuates significantly from cell to cell and from generation to generation. Here we …
often fluctuates significantly from cell to cell and from generation to generation. Here we …
[HTML][HTML] Efficient computation of stochastic cell-size transient dynamics
Background How small, fast-growing bacteria ensure tight cell-size distributions remains
elusive. High-throughput measurement techniques have propelled efforts to build modeling …
elusive. High-throughput measurement techniques have propelled efforts to build modeling …
Modeling cell size regulation: From single-cell-level statistics to molecular mechanisms and population-level effects
Most microorganisms regulate their cell size. In this article, we review some of the
mathematical formulations of the problem of cell size regulation. We focus on coarse …
mathematical formulations of the problem of cell size regulation. We focus on coarse …
Minimal requirements for robust cell size control in eukaryotic cells
Most cell types living in a stable environment tend to keep a constant characteristic size over
successive generations. Size homeostasis requires that cells exert a tight control over the …
successive generations. Size homeostasis requires that cells exert a tight control over the …
[HTML][HTML] Cell-size control and homeostasis in bacteria
How cells control their size and maintain size homeostasis is a fundamental open question.
Cell-size homeostasis has been discussed in the context of two major paradigms:" sizer," in …
Cell-size homeostasis has been discussed in the context of two major paradigms:" sizer," in …
[HTML][HTML] Mechanisms of cell size regulation in slow-growing Escherichia coli cells: discriminating models beyond the adder
Under ideal conditions, Escherichia coli cells divide after adding a fixed cell size, a strategy
known as the adder. This concept applies to various microbes and is often explained as the …
known as the adder. This concept applies to various microbes and is often explained as the …
[HTML][HTML] Size control in mammalian cells involves modulation of both growth rate and cell cycle duration
Despite decades of research, how mammalian cell size is controlled remains unclear
because of the difficulty of directly measuring growth at the single-cell level. Here we report …
because of the difficulty of directly measuring growth at the single-cell level. Here we report …
[HTML][HTML] Reassessment of the basis of cell size control based on analysis of cell-to-cell variability
Fundamental mechanisms governing cell size control and homeostasis are still poorly
understood. The relationship between sizes at division and birth in single cells is used as a …
understood. The relationship between sizes at division and birth in single cells is used as a …