[HTML][HTML] The translatability of multiple sclerosis animal models for biomarkers discovery and their clinical use
D Birmpili, I Charmarke Askar, K Bigaut… - International journal of …, 2022 - mdpi.com
Multiple Sclerosis (MS) is a chronic autoimmune disease affecting the central nervous
system which is characterized by demyelinating lesions and axonal damage. MS is a …
system which is characterized by demyelinating lesions and axonal damage. MS is a …
Preclinical models of multiple sclerosis: advantages and limitations towards better therapies
A Didonna - Current medicinal chemistry, 2016 - ingentaconnect.com
Multiple sclerosis (MS) is a disease of the central nervous system (CNS) with an unknown
etiology. MS complex pathophysiology—characterized by CNS inflammation, demyelination …
etiology. MS complex pathophysiology—characterized by CNS inflammation, demyelination …
Bridging the gap from genetic association to functional understanding: the next generation of mouse models of multiple sclerosis
KE Attfield, CA Dendrou, L Fugger - Immunological reviews, 2012 - Wiley Online Library
Multiple sclerosis (MS) is a disabling autoimmune disease of the central nervous system,
which affects approximately 0.1% of the population with variable degrees of severity …
which affects approximately 0.1% of the population with variable degrees of severity …
The value of animal models for drug development in multiple sclerosis
The rodent model for multiple sclerosis, experimental allergic (autoimmune)
encephalomyelitis (EAE), has been used to dissect molecular mechanisms of the …
encephalomyelitis (EAE), has been used to dissect molecular mechanisms of the …
The experimental autoimmune encephalomyelitis model for proteomic biomarker studies: from rat to human
T Rosenling, A Attali, TM Luider, R Bischoff - Clinica chimica acta, 2011 - Elsevier
Multiple sclerosis (MScl) is defined by central nervous system (CNS) inflammation,
demyelination and axonal damage. Some of the disease mechanisms are known but the …
demyelination and axonal damage. Some of the disease mechanisms are known but the …
Molecular mechanisms linking neuroinflammation and neurodegeneration in MS
E Ellwardt, F Zipp - Experimental neurology, 2014 - Elsevier
Multiple sclerosis (MS) is an inflammatory demyelinating autoimmune disorder of the central
nervous system (CNS) and one of the leading causes of neurological deficits and disability …
nervous system (CNS) and one of the leading causes of neurological deficits and disability …
[HTML][HTML] Molecular biomarkers in multiple sclerosis and its related disorders: A critical review
M Gul, A Azari Jafari, M Shah, S Mirmoeeni… - International journal of …, 2020 - mdpi.com
Multiple sclerosis (MS) is a chronic autoimmune disease affecting the central nervous
system (CNS) which can lead to severe disability. Several diseases can mimic the clinical …
system (CNS) which can lead to severe disability. Several diseases can mimic the clinical …
[HTML][HTML] Molecular biomarkers in multiple sclerosis
T Ziemssen, K Akgün, W Brück - Journal of neuroinflammation, 2019 - Springer
Multiple sclerosis (MS) is an inflammatory-neurodegenerative disease of the central nervous
system presenting with significant inter-and intraindividual heterogeneity. However, the …
system presenting with significant inter-and intraindividual heterogeneity. However, the …
From classic to spontaneous and humanized models of multiple sclerosis: impact on understanding pathogenesis and drug development
A Ben-Nun, N Kaushansky, N Kawakami… - Journal of …, 2014 - Elsevier
Multiple sclerosis (MS), a demyelinating disease of the central nervous system (CNS),
presents as a complex disease with variable clinical and pathological manifestations …
presents as a complex disease with variable clinical and pathological manifestations …
[HTML][HTML] Molecular models of multiple sclerosis severity identify heterogeneity of pathogenic mechanisms
P Kosa, C Barbour, M Varosanec, A Wichman… - Nature …, 2022 - nature.com
While autopsy studies identify many abnormalities in the central nervous system (CNS) of
subjects dying with neurological diseases, without their quantification in living subjects …
subjects dying with neurological diseases, without their quantification in living subjects …