The comparative survey of coordinated regulation of steroidogenic pathway in Japanese flounder (Paralichthys olivaceus) and Chinese tongue sole (Cynoglossus …

F Yang, Y Wang, W Lu, W Zong, Q Zhu… - International Journal of …, 2022 - mdpi.com
Steroidogenesis controls the conversion of cholesterol into steroid hormones through the
complex cascade reaction of various enzymes, which play essential roles in sexual …

Roles of two cyp11 genes in sex hormone biosynthesis in Japanese flounder (Paralichthys olivaceus)

L Meng, H Yu, F Ni, J Niu, X Liu… - Molecular Reproduction …, 2020 - Wiley Online Library
The P450 side‐chain cleavage enzymes P450scc (Cyp11a) and 11β‐hydroxylase (Cyp11b)
play important roles in sex steroid and cortisol production. Here, two duplicates of cyp11 …

Two cyp17 genes perform different functions in the sex hormone biosynthesis and gonadal differentiation in Japanese flounder (Paralichthys olivaceus)

L Meng, H Yu, J Qu, J Niu, F Ni, P Han, X Wang - Gene, 2019 - Elsevier
P450c17, a key enzyme in the steroid generation pathway, plays an important role in the
production of sex steroid and cortisol. In this study, two cyp17 gene isoforms, Pocyp17-I and …

Expression analysis of cyp11a1 during gonadal development, recrudescence and after hCG induction and sex steroid analog treatment in the catfish, Clarias …

A Rajakumar, B Senthilkumaran - … and Physiology Part B: Biochemistry and …, 2014 - Elsevier
In teleosts, the levels of steroids are critical for sexual development and hence, expression
of steroidogenic enzyme genes and specific substrate availability are indispensable for …

The roles of Cyp19ala and DMRT1 during gonadal sex differentiation and sex change in Orange-spotted grouper, Epinephelus coioides

CY Chen, YJ Tsai, CF Chang - Journal of Marine Science and …, 2019 - jmstt.ntou.edu.tw
Sex steroids play a crucial role in gonadal sex differentiation in many nonmammalian
vertebrates, including hermaphroditic teleosts. The current study investigates the mRNA …

Developmental expression of steroidogenic factor-1, cyp19a1a and cyp19a1b from common carp (Cyprinus carpio)

B Tang, W Hu, J Hao, Z Zhu - General and comparative endocrinology, 2010 - Elsevier
Steroidogenic factor-1 (SF-1), cyp19a1a and cyp19a1b play pivotal roles in vertebrate
steroidogenesis and reproduction. In this study, a SF-1 cDNA (EU022463) was cloned from …

Steroidogenic Effects of Salinity Change on the Hypothalamus–Pituitary–Gonad (HPG) Axis of Male Chinese Sea Bass (Lateolabrax maculatus)

Z Fang, X Li, Y Wang, W Lu, J Hou… - International Journal of …, 2022 - mdpi.com
As lower vertebrates, teleost species could be affected by dynamic aquatic environments
and may respond to environmental changes through the hypothalamus–pituitary–gonad …

Characterization of CYP11A1 and its potential role in sex asynchronous gonadal development of viviparous black rockfish Sebastes schlegelii (Sebastidae)

X Wang, H Wen, Y Li, L Lyu, M Song, Y Zhang… - General and …, 2021 - Elsevier
Mitochondrial cytochrome P450 side-chain cleavage (P450scc), encoded by the cyp11a1
gene, initiates the first step of steroid biosynthesis. In this study, a 1554-bp open reading …

Isolation of CYP17 I, 3β-HSD and AR Genes from Spotted Sea Bass (Lateolabrax maculatus) Testis and Their Responses to Hormones and Salinity Stimulations

M Chi, M Ni, Y Jia, Z Gu, H Wen - Journal of Ocean University of China, 2019 - Springer
In this study, three cDNA sequences corresponding to cytochrome P450C17 (CYP17 I), 3β-
hydroxysteroid dehydrogenase (3β-HSD) and androgen receptor (AR) were isolated from …

Steroidogenesis and its regulation in teleost-a review

A Rajakumar, B Senthilkumaran - Fish Physiology and Biochemistry, 2020 - Springer
Steroid hormones modulate several important biological processes like metabolism, stress
response, and reproduction. Steroidogenesis drives reproductive function wherein …