High avidity antibodies to full-length VAR2CSA correlate with absence of placental malaria
VAR2CSA mediates sequestration of Plasmodium falciparum-infected erythrocytes in the
placenta, increasing the risk of poor pregnancy outcomes. Naturally acquired antibodies …
placenta, increasing the risk of poor pregnancy outcomes. Naturally acquired antibodies …
High levels of antibodies to multiple domains and strains of VAR2CSA correlate with the absence of placental malaria in Cameroonian women living in an area of high …
YL Tutterrow, M Avril, K Singh, CA Long… - Infection and …, 2012 - Am Soc Microbiol
Placental malaria, caused by sequestration of Plasmodium falciparum-infected erythrocytes
in the placenta, is associated with increased risk of maternal morbidity and poor birth …
in the placenta, is associated with increased risk of maternal morbidity and poor birth …
VAR2CSA Domain-Specific Analysis of Naturally Acquired Functional Antibodies to Plasmodium falciparum Placental Malaria
JYA Doritchamou, R Herrera, JA Aebig… - The Journal of …, 2016 - academic.oup.com
Background. Placental malaria is caused by Plasmodium falciparum–infected erythrocytes
(IEs) that surface-express VAR2CSA and bind chondroitin sulfate A. The inflammatory …
(IEs) that surface-express VAR2CSA and bind chondroitin sulfate A. The inflammatory …
Comparison of the specificity of antibodies to VAR2CSA in Cameroonian multigravidae with and without placental malaria: a retrospective case–control study
Abstract Background Antibodies (Ab) to VAR2CSA prevent Plasmodium falciparum-infected
erythrocytes from sequestrating in the placenta, ie, prevent placental malaria (PM). The …
erythrocytes from sequestrating in the placenta, ie, prevent placental malaria (PM). The …
[HTML][HTML] A conserved epitope in VAR2CSA is targeted by a cross-reactive antibody originating from Plasmodium vivax Duffy binding protein
During Plasmodium falciparum infection in pregnancy, VAR2CSA is expressed on the
surface of infected erythrocytes (IEs) and mediates their sequestration in the placenta. As a …
surface of infected erythrocytes (IEs) and mediates their sequestration in the placenta. As a …
Induction of strain-transcendent antibodies to placental-type isolates with VAR2CSA DBL3 or DBL5 recombinant proteins
Background Pregnancy associated malaria is a severe clinical syndrome associated with
sequestration of Plasmodium falciparum-infected erythrocytes in the placenta. Placental …
sequestration of Plasmodium falciparum-infected erythrocytes in the placenta. Placental …
Antibodies to a full-length VAR2CSA immunogen are broadly strain-transcendent but do not cross-inhibit different placental-type parasite isolates
M Avril, MJ Hathaway, A Srivastava, S Dechavanne… - PloS one, 2011 - journals.plos.org
The high molecular weight, multidomain VAR2CSA protein mediating adhesion of
Plasmodium falciparum-infected erythrocytes in the placenta is the leading candidate for a …
Plasmodium falciparum-infected erythrocytes in the placenta is the leading candidate for a …
Var2CSA minimal CSA binding region is located within the N-terminal region
A Srivastava, S Gangnard, S Dechavanne, F Amirat… - PloS one, 2011 - journals.plos.org
Var2CSA, a key molecule linked with pregnancy-associated malaria (PAM), causes
sequestration of Plasmodium falciparum infected erythrocytes (PEs) in the placenta by …
sequestration of Plasmodium falciparum infected erythrocytes (PEs) in the placenta by …
Evidence for globally shared, cross-reacting polymorphic epitopes in the pregnancy-associated malaria vaccine candidate VAR2CSA
M Avril, BR Kulasekara, SO Gose, C Rowe… - Infection and …, 2008 - Am Soc Microbiol
Pregnancy-associated malaria (PAM) is characterized by the placental sequestration of
Plasmodium falciparum-infected erythrocytes (IEs) with the ability to bind to chondroitin …
Plasmodium falciparum-infected erythrocytes (IEs) with the ability to bind to chondroitin …
Cross-Species Immune Recognition Between Plasmodium vivax Duffy Binding Protein Antibodies and the Plasmodium falciparum Surface Antigen VAR2CSA
S Gnidehou, CJ Mitran, E Arango… - The Journal of …, 2019 - academic.oup.com
Abstract Background In pregnancy, Plasmodium falciparum parasites express the surface
antigen VAR2CSA, which mediates adherence of red blood cells to chondroitin sulfate A …
antigen VAR2CSA, which mediates adherence of red blood cells to chondroitin sulfate A …