DNA Framework‐Enabled Three Dimensional Organization of Antiarrhythmic Drugs for Radiofrequency Catheter Ablation
Pre‐organizing molecular drug within a microenvironment is crucial for the development of
efficient and controllable therapeutic systems. Here, we report the use of tetrahedral DNA …
efficient and controllable therapeutic systems. Here, we report the use of tetrahedral DNA …
Harnessing DNA origami's therapeutic potential for revolutionizing cardiovascular disease treatment: A comprehensive review
DNA origami is a cutting-edge nanotechnology approach that creates precise and detailed
2D and 3D nanostructures. The crucial feature of DNA origami is how it is created, which …
2D and 3D nanostructures. The crucial feature of DNA origami is how it is created, which …
Rational design of DNA framework‐based hybrid nanomaterials for anticancer drug delivery
Engineered DNA frameworks have been extensively exploited as affinity scaffolds for drug
delivery. However, few studies focus on the rational design to comprehensively improve …
delivery. However, few studies focus on the rational design to comprehensively improve …
3D-printed drug capture materials based on genomic DNA coatings
The toxic side effects of chemotherapy have long limited its efficacy, prompting expensive
and long-drawn efforts to develop more targeted cancer therapeutics. An alternative …
and long-drawn efforts to develop more targeted cancer therapeutics. An alternative …
Hierarchical fabrication of DNA wireframe nanoarchitectures for efficient cancer imaging and targeted therapy
Though small-molecule drugs play a crucial role in cancer treatment, intrinsic issues such as
poor solubility and systematic toxicity have considerably mitigated their anticancer functions …
poor solubility and systematic toxicity have considerably mitigated their anticancer functions …
A 3-D human model of complex cardiac arrhythmias
K Williams, T Liang, S Massé, S Khan, R Hatkar… - Acta Biomaterialia, 2021 - Elsevier
Cardiac arrhythmias impact over 12 million people globally, with an increasing incidence of
acquired arrhythmias. Although animal models have shed light onto fundamental arrhythmic …
acquired arrhythmias. Although animal models have shed light onto fundamental arrhythmic …
DNA‐based nanoarchitectures as eminent vehicles for smart drug delivery systems
M Komiyama, N Shigi, K Ariga - Advanced Functional Materials, 2022 - Wiley Online Library
In order to cure diseases efficiently with minimal side effects in sophisticated medicine,
eminent drugs must be selectively delivered to diseased parts and allow to work only there …
eminent drugs must be selectively delivered to diseased parts and allow to work only there …
Superlarge, Rigidified DNA Tetrahedron with a Y-Shaped Backbone for Organizing Biomolecules Spatially and Maintaining Their Full Bioactivity
W Wang, W Wang, Y Chen, M Lin, YR Chen, R Zeng… - ACS …, 2024 - ACS Publications
A major impediment to the clinical translation of DNA tiling nanostructures is a technical
bottleneck for the programmable assembly of DNA architectures with well-defined local …
bottleneck for the programmable assembly of DNA architectures with well-defined local …
Forging ahead: Update on radiofrequency ablation technology and techniques
Innovations in radiofrequency (RF) ablation and nonablative techniques have led to
significant advances in addressing complex arrhythmogenic substrates for a variety of …
significant advances in addressing complex arrhythmogenic substrates for a variety of …
Aptamer-conjugated DNA icosahedral nanoparticles as a carrier of doxorubicin for cancer therapy
M Chang, CS Yang, DM Huang - ACS nano, 2011 - ACS Publications
DNA can be used to nanofabricate three-dimensional (3D) polyhedra. A variety of
applications of 3D DNA assemblies have been proposed. Drug encasulation and …
applications of 3D DNA assemblies have been proposed. Drug encasulation and …