A woman's reproductive health and ability to have children directly affect numerous aspects
of her life, from personal well-being and socioeconomic standing, to morbidity and lifespan …

New thinking has arisen about the origin of adult onset diseases stemming from a collective
body of evidence commonly referred to as the developmental origins of health and disease …

Ovarian function in women can be compromised by exposure to toxic environmental factors.
Chemicals that affect ovarian function can act through direct effects on hormone action …

Background Because only 25% of cases of premature ovarian insufficiency (POI) have a
known etiology, the aim of this review was to summarize the associations and mechanisms …

Female reproductive function depends upon the exquisite control of ovarian steroidogenesis
that enables folliculogenesis, ovulation, and pregnancy. These mechanisms are set during …

The link between in utero and neonatal exposure to environmental toxicants, such as
endocrine-disrupting chemicals (EDCs) and adult female reproductive disorders is well …

The pathophysiological mechanisms underlying the origin of several ovarian pathologies
remain unclear. In addition to the genetic basis, developmental insults are gaining attention …

Oestrogens play an important role in development and function of the brain and reproductive
tract. Accordingly, it is considered that developmental exposure to environmental oestrogens …

The reproductive life span in women starts at puberty and ends at menopause, following the
exhaustion of the follicle stockpile termed the ovarian reserve. Increasing data from …

BACKGROUND Increased global industrial activity has exposed humans to a wide variety of
chemical substances some of which, called 'endocrine-disrupting chemicals'(EDCs) or …