Clinical evaluation of super-responders vs. non-responders to CGRP (-receptor) monoclonal antibodies: a real-world experience
B Raffaelli, M Fitzek, LH Overeem, E Storch… - The Journal of …, 2023 - Springer
Background Clinical trials and real-world studies revealed a spectrum of response to CGRP
(-receptor) monoclonal antibodies (mAbs) in migraine prophylaxis, ranging from no effect at …
(-receptor) monoclonal antibodies (mAbs) in migraine prophylaxis, ranging from no effect at …
Monoclonal antibodies blocking CGRP transmission: an update on their added value in migraine prevention
J Schoenen, M Manise, R Nonis, P Gérard… - Revue …, 2020 - Elsevier
The avenue of effective migraine therapies blocking calcitonin gene-related peptide (CGRP)
transmission is the successful outcome of 35 years of translational research. Developed …
transmission is the successful outcome of 35 years of translational research. Developed …
A scoping review and meta-analysis of anti-CGRP monoclonal antibodies: predicting response
JB Hong, KS Lange, LH Overeem, P Triller, B Raffaelli… - Pharmaceuticals, 2023 - mdpi.com
Calcitonin gene-related peptide-targeted monoclonal antibodies (CGRP mAbs) are
increasingly being used as preventive treatments for migraine. Their effectiveness and …
increasingly being used as preventive treatments for migraine. Their effectiveness and …
Deterioration of headache impact and health-related quality of life in migraine patients after cessation of preventive treatment with CGRP (− receptor) antibodies
M Terhart, J Mecklenburg, L Neeb, LH Overeem… - The Journal of …, 2021 - Springer
Background Migraine preventive treatment with CGRP (− receptor) monoclonal antibodies
(mAbs) has a positive effect on patients' health-related quality of life (HRQoL). The German …
(mAbs) has a positive effect on patients' health-related quality of life (HRQoL). The German …
Predictors of response to anti-CGRP monoclonal antibodies: a 24-week, multicenter, prospective study on 864 migraine patients
P Barbanti, G Egeo, C Aurilia, C Altamura… - The Journal of …, 2022 - Springer
Background and objectives The identification of predictors of response to antiCGRP mAbs
could favor tailored therapies and personalized treatment plans. This study is aimed at …
could favor tailored therapies and personalized treatment plans. This study is aimed at …
Long-term effectiveness of three anti-CGRP monoclonal antibodies in resistant chronic migraine patients based on the MIDAS score
Background Criteria, including clinical features and effective outcomes, for access and
persistence of novel but costly treatments may vary between countries, thus affecting the …
persistence of novel but costly treatments may vary between countries, thus affecting the …
CGRP monoclonal antibodies in migraine: an efficacy and tolerability comparison with standard prophylactic drugs
F Vandervorst, L Van Deun, A Van Dycke… - The journal of headache …, 2021 - Springer
Background Several drugs are available for the preventive treatment of both episodic and
chronic migraine. The choice of which therapy to initiate first, second, or third is not …
chronic migraine. The choice of which therapy to initiate first, second, or third is not …
CGRP antibody therapy in patients with drug resistant migraine and chronic daily headache: a real-world experience
A Scheffler, H Schenk, S Wurthmann, M Nsaka… - The Journal of …, 2021 - Springer
Background Calcitonin gene-related peptide (CGRP)(receptor) antibodies (erenumab,
fremanezumab and galcanezumab) are increasingly used in prophylactic treatment of …
fremanezumab and galcanezumab) are increasingly used in prophylactic treatment of …
Migraine evolution after the cessation of CGRP (-receptor) antibody prophylaxis: a prospective, longitudinal cohort study
B Raffaelli, M Terhart, LH Overeem… - …, 2022 - journals.sagepub.com
Background National and international guidelines recommend stopping migraine
prophylaxis with CGRP (-receptor) monoclonal antibodies after 6–12 months of successful …
prophylaxis with CGRP (-receptor) monoclonal antibodies after 6–12 months of successful …
Efficacy and contextual (placebo) effects of CGRP antibodies for migraine: systematic review and meta‐analysis
RB Forbes, M McCarron… - Headache: The Journal …, 2020 - Wiley Online Library
Background CGRP Antibodies are high‐cost newly licensed migraine preventatives.
Objective To calculate the overall reduction in monthly migraine days and the proportion …
Objective To calculate the overall reduction in monthly migraine days and the proportion …