Clinical evaluation of super-responders vs. non-responders to CGRP (-receptor) monoclonal antibodies: a real-world experience

B Raffaelli, M Fitzek, LH Overeem, E Storch… - The Journal of …, 2023 - Springer
Background Clinical trials and real-world studies revealed a spectrum of response to CGRP
(-receptor) monoclonal antibodies (mAbs) in migraine prophylaxis, ranging from no effect at …

Monoclonal antibodies blocking CGRP transmission: an update on their added value in migraine prevention

J Schoenen, M Manise, R Nonis, P Gérard… - Revue …, 2020 - Elsevier
The avenue of effective migraine therapies blocking calcitonin gene-related peptide (CGRP)
transmission is the successful outcome of 35 years of translational research. Developed …

A scoping review and meta-analysis of anti-CGRP monoclonal antibodies: predicting response

JB Hong, KS Lange, LH Overeem, P Triller, B Raffaelli… - Pharmaceuticals, 2023 - mdpi.com
Calcitonin gene-related peptide-targeted monoclonal antibodies (CGRP mAbs) are
increasingly being used as preventive treatments for migraine. Their effectiveness and …

Deterioration of headache impact and health-related quality of life in migraine patients after cessation of preventive treatment with CGRP (− receptor) antibodies

M Terhart, J Mecklenburg, L Neeb, LH Overeem… - The Journal of …, 2021 - Springer
Background Migraine preventive treatment with CGRP (− receptor) monoclonal antibodies
(mAbs) has a positive effect on patients' health-related quality of life (HRQoL). The German …

Predictors of response to anti-CGRP monoclonal antibodies: a 24-week, multicenter, prospective study on 864 migraine patients

P Barbanti, G Egeo, C Aurilia, C Altamura… - The Journal of …, 2022 - Springer
Background and objectives The identification of predictors of response to antiCGRP mAbs
could favor tailored therapies and personalized treatment plans. This study is aimed at …

Long-term effectiveness of three anti-CGRP monoclonal antibodies in resistant chronic migraine patients based on the MIDAS score

LF Iannone, D Fattori, S Benemei, A Chiarugi… - CNS drugs, 2022 - Springer
Background Criteria, including clinical features and effective outcomes, for access and
persistence of novel but costly treatments may vary between countries, thus affecting the …

CGRP monoclonal antibodies in migraine: an efficacy and tolerability comparison with standard prophylactic drugs

F Vandervorst, L Van Deun, A Van Dycke… - The journal of headache …, 2021 - Springer
Background Several drugs are available for the preventive treatment of both episodic and
chronic migraine. The choice of which therapy to initiate first, second, or third is not …

CGRP antibody therapy in patients with drug resistant migraine and chronic daily headache: a real-world experience

A Scheffler, H Schenk, S Wurthmann, M Nsaka… - The Journal of …, 2021 - Springer
Background Calcitonin gene-related peptide (CGRP)(receptor) antibodies (erenumab,
fremanezumab and galcanezumab) are increasingly used in prophylactic treatment of …

Migraine evolution after the cessation of CGRP (-receptor) antibody prophylaxis: a prospective, longitudinal cohort study

B Raffaelli, M Terhart, LH Overeem… - …, 2022 - journals.sagepub.com
Background National and international guidelines recommend stopping migraine
prophylaxis with CGRP (-receptor) monoclonal antibodies after 6–12 months of successful …

Efficacy and contextual (placebo) effects of CGRP antibodies for migraine: systematic review and meta‐analysis

RB Forbes, M McCarron… - Headache: The Journal …, 2020 - Wiley Online Library
Background CGRP Antibodies are high‐cost newly licensed migraine preventatives.
Objective To calculate the overall reduction in monthly migraine days and the proportion …