Toward miniaturized analysis of chemical identity and purity of radiopharmaceuticals via microchip electrophoresis
J Ly, NS Ha, S Cheung, RM van Dam - Analytical and bioanalytical …, 2018 - Springer
Miniaturized synthesis of positron emission tomography (PET) tracers is poised to offer
numerous advantages including reduced tracer production costs and increased availability …
numerous advantages including reduced tracer production costs and increased availability …
Integration of high-resolution radiation detector for hybrid microchip electrophoresis
J Jones, NS Ha, AG Barajas… - Analytical …, 2020 - ACS Publications
For decades, there has been immense progress in miniaturizing analytical methods based
on electrophoresis to improve sensitivity and to reduce sample volumes, separation times …
on electrophoresis to improve sensitivity and to reduce sample volumes, separation times …
Novel volumetric method for highly repeatable injection in microchip electrophoresis
NS Ha, J Ly, J Jones, S Cheung, RM van Dam - Analytica chimica acta, 2017 - Elsevier
A novel injector for microchip electrophoresis (MCE) has been designed and evaluated that
achieves very high repeatability of injection volume suitable for quantitative analysis. It …
achieves very high repeatability of injection volume suitable for quantitative analysis. It …
Microfluidics: a groundbreaking technology for PET tracer production?
C Rensch, A Jackson, S Lindner, R Salvamoser… - Molecules, 2013 - mdpi.com
Application of microfluidics to Positron Emission Tomography (PET) tracer synthesis has
attracted increasing interest within the last decade. The technical advantages of …
attracted increasing interest within the last decade. The technical advantages of …
Recent progress toward microfluidic quality control testing of radiopharmaceuticals
NS Ha, S Sadeghi, RM Van Dam - Micromachines, 2017 - mdpi.com
Radiopharmaceuticals labeled with short-lived positron-emitting or gamma-emitting isotopes
are injected into patients just prior to performing positron emission tomography (PET) or …
are injected into patients just prior to performing positron emission tomography (PET) or …
Microfluidic synthesis of radiotracers: recent developments and commercialization prospects
M Mc Veigh, LM Bellan - Lab on a Chip, 2024 - pubs.rsc.org
Positron emission tomography (PET) is a powerful diagnostic tool that holds incredible
potential for clinicians to track a wide variety of biological processes using specialized …
potential for clinicians to track a wide variety of biological processes using specialized …
Recent applications of microchip electrophoresis to biomedical analysis
Many separation methods have been developed for biomedical analysis, including
chromatographic (eg high performance liquid chromatography (HPLC) and gas …
chromatographic (eg high performance liquid chromatography (HPLC) and gas …
Microchip electrophoresis with hydrodynamic injection and waste-removing function for quantitative analysis
CC Lin, CC Chen, CE Lin, SH Chen - Journal of Chromatography A, 2004 - Elsevier
Quantitative analysis is problematic for microchip electrophoresis for several reasons
including chip-to-chip variation, discontinuous sample re-loading, channel reconditioning …
including chip-to-chip variation, discontinuous sample re-loading, channel reconditioning …
Automatic concentration and reformulation of PET tracers via microfluidic membrane distillation
PH Chao, J Collins, JP Argus, WY Tseng, JT Lee… - Lab on a Chip, 2017 - pubs.rsc.org
Short-lived radiolabeled tracers for positron emission tomography (PET) must be rapidly
synthesized, purified, and formulated into injectable solution just prior to imaging. Current …
synthesized, purified, and formulated into injectable solution just prior to imaging. Current …
Compact microfluidic device for rapid concentration of PET tracers
WY Tseng, RM van Dam - Lab on a Chip, 2014 - pubs.rsc.org
HPLC purification and reformulation of positron emission tomography (PET) tracers can lead
to significant dilution of the final product, making it difficult to produce a sufficiently high …
to significant dilution of the final product, making it difficult to produce a sufficiently high …
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