lncRNA involvement in cancer stem cell function and epithelial-mesenchymal transitions
EM McCabe, TP Rasmussen - Seminars in cancer biology, 2021 - Elsevier
Epithelial to mesenchymal transition (EMT) is a cellular process in which cells composing
epithelial tissue lose requirements for physical contact with neighboring cells and acquire …
epithelial tissue lose requirements for physical contact with neighboring cells and acquire …
Insights into biological role of LncRNAs in epithelial-mesenchymal transition
Long non-coding RNAs (lncRNAs) are versatile regulators of gene expression and play
crucial roles in diverse biological processes. Epithelial-mesenchymal transition (EMT) is a …
crucial roles in diverse biological processes. Epithelial-mesenchymal transition (EMT) is a …
Long non-coding RNAs: key regulators of epithelial-mesenchymal transition, tumour drug resistance and cancer stem cells
Epithelial mesenchymal transition (EMT), the adoption by epithelial cells of a mesenchymal-
like phenotype, is a process co-opted by carcinoma cells in order to initiate invasion and …
like phenotype, is a process co-opted by carcinoma cells in order to initiate invasion and …
The emerging role of lncRNAs in the regulation of cancer stem cells
R Castro-Oropeza, J Melendez-Zajgla, V Maldonado… - Cellular Oncology, 2018 - Springer
Background Tumors contain a functional subpopulation of cells that exhibit stem cell
properties. These cells, named cancer stem cells (CSCs), play significant roles in the …
properties. These cells, named cancer stem cells (CSCs), play significant roles in the …
Long non-coding RNA regulation of epithelial–mesenchymal transition in cancer metastasis
Q Xu, F Deng, Y Qin, Z Zhao, Z Wu, Z Xing, A Ji… - Cell death & …, 2016 - nature.com
Metastasis is a multistep process starting with the dissemination of tumor cells from a
primary site and ending with secondary tumor development in an anatomically distant …
primary site and ending with secondary tumor development in an anatomically distant …
Long noncoding RNA and epithelial mesenchymal transition in cancer
M Gugnoni, A Ciarrocchi - International journal of molecular sciences, 2019 - mdpi.com
Epithelial–mesenchymal transition (EMT) is a multistep process that allows epithelial cells to
acquire mesenchymal properties. Fundamental in the early stages of embryonic …
acquire mesenchymal properties. Fundamental in the early stages of embryonic …
The expanding roles of long non-coding RNAs in the regulation of cancer stem cells
Long non-coding RNAs (lncRNAs) are a novel class of gene regulators playing multifaceted
roles in physiological processes as well as pathological conditions such as cancer. Cancer …
roles in physiological processes as well as pathological conditions such as cancer. Cancer …
Exploring the roles of lncRNAs in GBM pathophysiology and their therapeutic potential
CT Stackhouse, GY Gillespie, CD Willey - Cells, 2020 - mdpi.com
Glioblastoma (GBM) remains the most devastating primary central nervous system
malignancy with a median survival of around 15 months. The past decades of research have …
malignancy with a median survival of around 15 months. The past decades of research have …
Non-coding RNAs and epithelial mesenchymal transition in cancer: molecular mechanisms and clinical implications
H Khanbabaei, S Ebrahimi… - Journal of Experimental …, 2022 - Springer
Epithelial-mesenchymal transition (EMT) is a fundamental process for embryonic
development during which epithelial cells acquire mesenchymal characteristics, and the …
development during which epithelial cells acquire mesenchymal characteristics, and the …
From junk to master regulators of invasion: lncRNA functions in migration, EMT and metastasis
S Dhamija, S Diederichs - International journal of cancer, 2016 - Wiley Online Library
Metastasis is a multistep process that involves the dissemination of cells from the primary
tumor and colonization of distant secondary organs. Epithelial cells at the invasive front of a …
tumor and colonization of distant secondary organs. Epithelial cells at the invasive front of a …