Comparative efficacy and tolerability of 32 oral and long-acting injectable antipsychotics for the maintenance treatment of adults with schizophrenia: a systematic …

J Schneider-Thoma, K Chalkou, C Dörries, I Bighelli… - The lancet, 2022 - thelancet.com
Background Schizophrenia is a common, severe, and usually chronic disorder. Maintenance
treatment with antipsychotic drugs can prevent relapse but also causes side-effects. We …

Long-acting injectable versus oral antipsychotics for the maintenance treatment of schizophrenia: a systematic review and comparative meta-analysis of randomised …

T Kishimoto, K Hagi, S Kurokawa, JM Kane… - The Lancet …, 2021 - thelancet.com
Background Evidence of comparative benefits of long-acting injectable antipsychotics (LAIs)
versus oral antipsychotics for schizophrenia has been inconsistent across study designs …

Continuing, reducing, switching, or stopping antipsychotics in individuals with schizophrenia-spectrum disorders who are clinically stable: a systematic review and …

G Ostuzzi, G Vita, F Bertolini, F Tedeschi… - The Lancet …, 2022 - thelancet.com
Background Although antipsychotic maintenance treatment is widely recommended to
prevent relapse in chronic psychoses, evidence-based guidelines do not provide clear …

Standard versus reduced dose of antipsychotics for relapse prevention in multi-episode schizophrenia: a systematic review and meta-analysis of randomised …

M Højlund, AF Kemp, PM Haddad, JC Neill… - The Lancet …, 2021 - thelancet.com
Background Dose reduction of antipsychotic maintenance treatment in individuals with
schizophrenia could be desirable to minimise adverse effects, but evidence for this strategy …

Antipsychotic treatment in the maintenance phase of schizophrenia: an updated systematic review of the guidelines and algorithms

Y Shimomura, Y Kikuchi, T Suzuki, H Uchida… - Schizophrenia …, 2020 - Elsevier
Background We updated our previous systematic review regarding clinical guidelines and
algorithms on antipsychotic treatment in the maintenance phase of schizophrenia (doi …

Relapse prevention in schizophrenia with new-generation antipsychotics: a systematic review and exploratory meta-analysis of randomized, controlled trials

S Leucht, TRE Barnes, W Kissling… - American Journal of …, 2003 - Am Psychiatric Assoc
OBJECTIVE: The authors performed a systematic review and meta-analysis of studies of the
potential of new-generation antipsychotic drugs to improve adherence and decrease …

Antipsychotic treatment for schizophrenia in the maintenance phase: a systematic review of the guidelines and algorithms

H Takeuchi, T Suzuki, H Uchida, K Watanabe… - Schizophrenia …, 2012 - Elsevier
OBJECTIVE: Antipsychotic treatment strategy for the maintenance phase of schizophrenia
has been inconsistent in the literature. The purpose of this systematic review is to overview …

Oral and long‐acting antipsychotics for relapse prevention in schizophrenia‐spectrum disorders: a network meta‐analysis of 92 randomized trials including 22,645 …

G Ostuzzi, F Bertolini, F Tedeschi, G Vita… - World …, 2022 - Wiley Online Library
According to current evidence and guidelines, continued antipsychotic treatment is key for
preventing relapse in people with schizophrenia‐spectrum disorders, but evidence‐based …

The use of continuous treatment versus placebo or intermittent treatment strategies in stabilized patients with schizophrenia: a systematic review and meta-analysis of …

M De Hert, J Sermon, P Geerts, K Vansteelandt… - CNS drugs, 2015 - Springer
Background Although continuous treatment with antipsychotics is still recommended as the
gold standard treatment paradigm for all patients with schizophrenia, some clinicians …

Antipsychotic drugs versus placebo for relapse prevention in schizophrenia: a systematic review and meta-analysis

S Leucht, M Tardy, K Komossa, S Heres, W Kissling… - The Lancet, 2012 - thelancet.com
Background Relapse prevention with antipsychotic drugs compared with placebo in patients
with schizophrenia has not been sufficiently addressed by previous systematic reviews. We …