Advances of mesenchymal stem cells and their derived extracellular vesicles as a promising therapy for acute respiratory distress syndrome: from bench to clinic

X Zhuang, Y Jiang, X Yang, L Fu, L Luo… - Frontiers in …, 2023 - frontiersin.org
Acute respiratory distress syndrome (ARDS) is an acute inflammatory lung injury
characterized by diffuse alveolar damage. The period prevalence of ARDS was 10.4% of …

Mesenchymal stem cells-derived extracellular vesicles in acute respiratory distress syndrome: a review of current literature and potential future treatment options

TG Shah, D Predescu, S Predescu - Clinical and Translational Medicine, 2019 - Springer
Acute respiratory distress syndrome (ARDS) is a life-threatening inflammatory lung condition
associated with significant morbidity and mortality. Unfortunately, the current treatment for …

Extracellular vesicles derived from mesenchymal stem cells: a potential biodrug for acute respiratory distress syndrome treatment

H Sun, T Zhang, J Gao - BioDrugs, 2022 - Springer
Acute respiratory distress syndrome (ARDS) is a severe respiratory disease associated with
high morbidity and mortality in the clinic. In the face of limited treatment options for ARDS …

Mesenchymal stem cell-derived extracellular vesicles for the treatment of acute respiratory distress syndrome

A Abraham, A Krasnodembskaya - Stem Cells Translational …, 2020 - academic.oup.com
Acute respiratory distress syndrome (ARDS) is a serious and potentially fatal acute
inflammatory lung condition which currently has no specific treatments targeting its …

Therapeutic use of mesenchymal stem cell–derived extracellular vesicles in acute lung injury

JH Lee, J Park, JW Lee - Transfusion, 2019 - Wiley Online Library
Acute respiratory distress syndrome is a major cause of respiratory failure in critically ill
patients. Despite extensive research into its pathophysiology, mortality remains high. No …

Mesenchymal stem cell derived secretome and extracellular vesicles for acute lung injury and other inflammatory lung diseases

A Monsel, Y Zhu, V Gudapati, H Lim… - Expert opinion on …, 2016 - Taylor & Francis
Introduction: Acute respiratory distress syndrome is a major cause of respiratory failure in
critically ill patients. Despite extensive research into its pathophysiology, mortality remains …

Effects of mesenchymal stromal cell-derived extracellular vesicles in acute respiratory distress syndrome (ARDS): current understanding and future perspectives

Y Su, H Guo, Q Liu - Journal of leukocyte biology, 2021 - academic.oup.com
Acute respiratory distress syndrome (ARDS) is a devastating and life-threatening syndrome
that results in high morbidity and mortality. Current pharmacologic treatments and …

Therapeutic potential of mesenchymal stem/stromal cell-derived secretome and vesicles for lung injury and disease

A Liu, X Zhang, H He, L Zhou, Y Naito… - Expert opinion on …, 2020 - Taylor & Francis
Introduction: The acute respiratory distress syndrome (ARDS) is a devastating clinical
condition common in patients with respiratory failure. Based largely on numerous preclinical …

Mesenchymal stem cell-based therapy as an alternative to the treatment of acute respiratory distress syndrome: current evidence and future perspectives

S Fernández-Francos, N Eiro… - International journal of …, 2021 - mdpi.com
Acute respiratory distress syndrome (ARDS) represents a current challenge for medicine
due to its incidence, morbidity and mortality and, also, the absence of an optimal treatment …

Mesenchymal stem cell-derived exosomes for treatment of sepsis

K Homma, N Bazhanov, K Hashimoto… - Frontiers in …, 2023 - frontiersin.org
Introduction The pathogenesis of sepsis is an imbalance between pro-inflammatory and anti-
inflammatory responses. At the onset of sepsis, the lungs are severely affected, and the …