The generation of vesicles is a constitutive attribute of mitochondria inherited from bacterial
ancestors. The physiological conditions and mild oxidative stress promote oxidation and …

Mitochondria are central hubs of cellular metabolism and are tightly connected to signaling
pathways. The dynamic plasticity of mitochondria to fuse, divide, and contact other …

Mitochondrial quality control (MQC) mechanisms are a series of adaptive responses that
ensure the relative stability of mitochondrial morphology, quantity, and quality to preserve …

Mitochondria are dynamic organelles regulating metabolism, cell death, and energy
production. Therefore, maintaining mitochondrial health is critical for cellular homeostasis …

The mitochondria play a crucial role in cellular metabolism, reactive oxygen species (ROS)
production, and apoptosis. Aberrant mitochondria can cause severe damage to the cells …

Mitophagy is crucial for maintaining mitochondrial quality. However, its assessment in vivo is
challenging. The endosomal–lysosomal system is a more accessible pathway through …

Key points Mitochondrial‐derived vesicle (MDV) formation occurs under baseline conditions
and is rapidly upregulated in response to stress‐inducing conditions in H9c2 cardiac …

Mitochondria are intracellular organelles involved in a myriad of activities. To safeguard their
vital functions, mitochondrial quality control (MQC) systems are in place to support organelle …

Mitochondrial damage plays vital roles in the pathology of many diseases, such as cancers,
neurodegenerative diseases, aging, metabolic diseases and many types of organ injury …

The last decade has been marked by tremendous progress in our understanding of the cell
biology of mitochondria, with the identification of molecules and mechanisms that regulate …