[HTML][HTML] The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts
AG Baltz, M Munschauer, B Schwanhäusser, A Vasile… - Molecular cell, 2012 - cell.com
Protein-RNA interactions are fundamental to core biological processes, such as mRNA
splicing, localization, degradation, and translation. We developed a photoreactive …
splicing, localization, degradation, and translation. We developed a photoreactive …
[HTML][HTML] Insights into RNA biology from an atlas of mammalian mRNA-binding proteins
A Castello, B Fischer, K Eichelbaum, R Horos… - Cell, 2012 - cell.com
RNA-binding proteins (RBPs) determine RNA fate from synthesis to decay. Employing two
complementary protocols for covalent UV crosslinking of RBPs to RNA, we describe a …
complementary protocols for covalent UV crosslinking of RBPs to RNA, we describe a …
[HTML][HTML] Differential protein occupancy profiling of the mRNA transcriptome
Background RNA-binding proteins (RBPs) mediate mRNA biogenesis, translation and
decay. We recently developed an approach to profile transcriptome-wide RBP contacts on …
decay. We recently developed an approach to profile transcriptome-wide RBP contacts on …
[HTML][HTML] Pervasive and dynamic protein binding sites of the mRNA transcriptome in Saccharomyces cerevisiae
Background Protein-RNA interactions are integral components of nearly every aspect of
biology, including regulation of gene expression, assembly of cellular architectures, and …
biology, including regulation of gene expression, assembly of cellular architectures, and …
Quantification and discovery of sequence determinants of protein‐per‐mRNA amount in 29 human tissues
Despite their importance in determining protein abundance, a comprehensive catalogue of
sequence features controlling protein‐to‐mRNA (PTR) ratios and a quantification of their …
sequence features controlling protein‐to‐mRNA (PTR) ratios and a quantification of their …
Unbiased RNA–protein interaction screen by quantitative proteomics
F Butter, M Scheibe, M Mörl… - Proceedings of the …, 2009 - National Acad Sciences
Mass spectrometry (MS)-based quantitative interaction proteomics has successfully
elucidated specific protein–protein, DNA–protein, and small molecule–protein interactions …
elucidated specific protein–protein, DNA–protein, and small molecule–protein interactions …
[HTML][HTML] Quantitative profiling of in vivo-assembled RNA-protein complexes using a novel integrated proteomic approach
BP Tsai, X Wang, L Huang, ML Waterman - Molecular & Cellular Proteomics, 2011 - ASBMB
Identification of proteins in RNA-protein complexes is an important step toward
understanding regulation of RNA-based processes. Because of the lack of appropriate …
understanding regulation of RNA-based processes. Because of the lack of appropriate …
[HTML][HTML] Systematic discovery of endogenous human ribonucleoprotein complexes
RNA-binding proteins (RBPs) play essential roles in biology and are frequently associated
with human disease. Although recent studies have systematically identified individual RNA …
with human disease. Although recent studies have systematically identified individual RNA …
[HTML][HTML] Changes in mRNA abundance drive shuttling of RNA binding proteins, linking cytoplasmic RNA degradation to transcription
S Gilbertson, JD Federspiel, E Hartenian, IM Cristea… - elife, 2018 - elifesciences.org
Alterations in global mRNA decay broadly impact multiple stages of gene expression,
although signals that connect these processes are incompletely defined. Here, we used …
although signals that connect these processes are incompletely defined. Here, we used …
Isoform‐resolved correlation analysis between mRNA abundance regulation and protein level degradation
Profiling of biological relationships between different molecular layers dissects regulatory
mechanisms that ultimately determine cellular function. To thoroughly assess the role of …
mechanisms that ultimately determine cellular function. To thoroughly assess the role of …