[HTML][HTML] Formation and diversification of a paradigm biosynthetic gene cluster in plants
Numerous examples of biosynthetic gene clusters (BGCs), including for compounds of
agricultural and medicinal importance, have now been discovered in plant genomes …
agricultural and medicinal importance, have now been discovered in plant genomes …
[HTML][HTML] New and emerging concepts in the evolution and function of plant biosynthetic gene clusters
G Polturak, Z Liu, A Osbourn - Current Opinion in Green and Sustainable …, 2022 - Elsevier
Plants are a rich source of diverse chemicals. Metabolic diversification is likely a reflection of
adaptation to particular environmental niches because many of these compounds are …
adaptation to particular environmental niches because many of these compounds are …
[HTML][HTML] Plant biosynthetic gene clusters in the context of metabolic evolution
SJ Smit, BR Lichman - Natural Product Reports, 2022 - pubs.rsc.org
Covering: up to 2022 Plants produce a wide range of structurally and biosynthetically
diverse natural products to interact with their environment. These specialised metabolites …
diverse natural products to interact with their environment. These specialised metabolites …
[HTML][HTML] Plant metabolic gene clusters: evolution, organization, and their applications in synthetic biology
R Bharadwaj, SR Kumar, A Sharma… - Frontiers in Plant …, 2021 - frontiersin.org
Plants are a remarkable source of high-value specialized metabolites having significant
physiological and ecological functions. Genes responsible for synthesizing specialized …
physiological and ecological functions. Genes responsible for synthesizing specialized …
Plant metabolic gene clusters in the multi-omics era
Secondary metabolism in plants gives rise to a vast array of small-molecule natural
products. The discovery of operon-like gene clusters in plants has provided a new …
products. The discovery of operon-like gene clusters in plants has provided a new …
Metabolic diversification—independent assembly of operon-like gene clusters in different plants
B Field, AE Osbourn - Science, 2008 - science.org
Operons are clusters of unrelated genes with related functions that are a feature of
prokaryotic genomes. Here, we report on an operon-like gene cluster in the plant …
prokaryotic genomes. Here, we report on an operon-like gene cluster in the plant …
Formation of plant metabolic gene clusters within dynamic chromosomal regions
In bacteria, genes with related functions often are grouped together in operons and are
cotranscribed as a single polycistronic mRNA. In eukaryotes, functionally related genes …
cotranscribed as a single polycistronic mRNA. In eukaryotes, functionally related genes …
[HTML][HTML] Gene clustering in plant specialized metabolism
HW Nützmann, A Osbourn - Current opinion in biotechnology, 2014 - Elsevier
Highlights•Physical clustering of genes for specialized metabolic pathways is common in
plants.•The common and individual features of plant metabolic gene clusters are …
plants.•The common and individual features of plant metabolic gene clusters are …
Something old, something new: conserved enzymes and the evolution of novelty in plant specialized metabolism
Plants produce hundreds of thousands of small molecules known as specialized
metabolites, many of which are of economic and ecological importance. This remarkable …
metabolites, many of which are of economic and ecological importance. This remarkable …
Making new molecules–evolution of pathways for novel metabolites in plants
DJ Kliebenstein, A Osbourn - Current opinion in plant biology, 2012 - Elsevier
Plants have adapted to their environments by diversifying in various ways. This
diversification is reflected at the phytochemical level in their production of numerous …
diversification is reflected at the phytochemical level in their production of numerous …