Background and purpose: Acetaminophen is a routine analgesic and antipyretic agent that
in overdose causes liver and kidney necrosis in both humans and animals. The cress …

Objectives: Acetaminophen can cause liver damage that can result with death when it is
taken as high doses. In our study we proposed to examine the silymarin effect on …

Introduction Acetaminophen (APAP) as an analgesic and antipyretic drug can result to liver
damages while using more than 4 g/day. Therefore, APAP toxicity causes the liver to …

Objectives: Acetaminophen (APAP) toxicity is known to be common and potentially fatal.
This study aims to investigate the protective effects of hydroalcoholic extract, remaining from …

Background: Although acetaminophen (APAP) is considered safe at therapeutic doses,
intake of high amounts of this drug can cause liver failure. In the present experiment, we …

Materials and Methods: This is an experimental study in which fifty six NMRI male mice were
randomly divided into 7 groups. After one night fasting, normal saline was given to the first …

Background & Objective: Acetaminophen is a widely used analgesic and antipyretic drug
which can produce hepatic injury in both humans and animals when given in high doses …

Materials and Methods: In this study, 30 male rats were allocated into five groups of six in
number as follows: control, acetaminophen (A), and acetaminophen+ C. cyminum 200, 400 …

ABSTRACT Address for Correspondence: Dr. Jeneth Berlin Raj, Professor, Department of
Physiology, Mahatma Gandhi Medical College & Research Institute, Sri Balaji Vidyapeeth …

Regarding highly prescription of medicines, in recent years, herbal effects on prevention and
treatment of toxicity induced by various drugs have received a great deal of attention. After …