Background and objective Although, the anti-depressant like effects of apigenin (APG) are
documented in the literature, the underlying mechanism for exerting such an effect is still not …

This study aimed to examine the antidepressant properties of apigenin in an experimental
mouse model of chronic mild stress (CMS). Three weeks following CMS, albino mice of …

Previous researches found that apigenin exerted antidepressant-like effects in rodents.
However, it is unclear whether the neurotrophic system is involved in the antidepressant-like …

Apigenin is a flavone widely present in different fruits and vegetables and has been
suggested to possess neuroprotective effects against some neurological disorders. In this …

Apigenin (4′, 5, 7-trihydroxyflavone) is a dietary flavonoid that is abundantly present in
many fruits, medicinal herbs, vegetables and formally belongs to the flavone sub-class. 1 …

Although bupropion has been widely used in the treatment of depression, the precise
mechanism of its therapeutic actions is not fully understood. The present study investigated …

Abstract Ethnopharmacological relevance Aloysia gratissima (Verbenaceae) is an aromatic
plant distributed in South America and, employed in folk medicine for the treatment of …

Trans-anethole (ANE) is a monoterpene present in many aromatic plants, especially
Pimpinella anisum (PA). In this regard, we previously reported the anti-depressant potential …

This study investigated the involvement of 5-HT1 and 5-HT2 receptors in the antidepressant-
like effect of agmatine in the mouse forced swimming test (FST). Pretreatment with p …

Rationale Depression is common in Parkinson's disease (PD) but its response to classical
antidepressants is not clear. The adenosine A 2A antagonist istradefylline is effective in the …