Objectives: Chordoma is a rare bone malignancy that affects the spine and skull base.
Treatment dilemma leads to a high rate of local relapse and distant metastases. Molecular …

Background Chordoma is a rare malignant tumor of the skull base and axial skeleton, with
an incidence of less than 0.1/100,000 per year. Patients with advanced chordoma have a …

Chordoma is a very rare bone sarcoma that can arise from any site along the spine and from
the skull base. En bloc resection is the gold standard for treatment while radiation therapy …

Background To assess the role of first-line Molecular Targeted Therapies (MTTs) in
Advanced chordoma (AC) patients. Methods Retrospective study of 80 patients treated …

Introduction Despite encouraging advances in radiation and surgical treatment, chordomas
remain resistant to chemotherapy and local recurrence is common. Although the primary …

Chordomas are rare, malignant bone tumors of the skull-base and axial skeleton. Until
recently, there was no consensus among experts regarding appropriate clinical …

Chordoma is an extremely rare cancer, with an incidence of about one case per million
persons per year in the USA and Europe (about 300 and 450 cases per year, respectively) …

Background Chordomas are very rare low-grade malignant bone tumors that arise from the
embryonic rests of the notochord. They are characterized by slow growth and long history …

Simple Summary Surgery is the primary treatment for chordoma. However, residual or
recurrent chordoma presents a significant problem for clinicians. The aim of this work is to …

Chordomas are very rare bone malignant tumours that have had a shortage of effective
treatments for a long time. New treatments are now available for both the local and the …