Drosophila melanogaster is a valuable model organism for a wide range of biological
exploration. The well-known advantages of D. melanogaster include its relatively simple …

Highlights•Parkinson's Disease (PD) affects motor functions of individual.•Accumulation of
senescent cells (SC) deteriorate the pathological cascade of PD.•SC secrete components …

Parkinson's disease (PD) is a common neurodegenerative disorder characterized by
selective and progressive loss of dopaminergic neurons. Genetic and environmental risk …

The power of Drosophila genetics has attracted attention in tackling important biomedical
challenges such as the understanding and prevention of neurodegenerative diseases …

Parkinson's disease (PD) is the second most common neurodegenerative disorder affecting
approximately 1% of the population over age 50. PD is widely accepted as a multifactorial …

Parkinson's disease (PD) affects almost 1% of the population worldwide over the age of 50
years. Exposure to environmental toxins like paraquat and rotenone is a risk factor for …

Despite the prevalence and severity of Parkinson's disease (PD), little is known about the
molecular etiology of this disease, and preventative and disease-modifying therapies remain …

Background Protein aggregation in neurons is a prominent pathological mark of
neurodegeneration. In Parkinson's disease (PD), inclusions of the α-Synuclein (α-Syn) …

Background In the past decade, the study of the pathogenic mechanisms underlying
neurodegeneration in Parkinson's disease (PD) has revealed a genetic component, often …

Importance of the field: Parkinson's disease (PD) is a prevalent neurodegenerative disease
affecting millions of predominantly elderly individuals worldwide. Despite intensive efforts …