Objective: Specialized sensory epithelial cells sensing noxious chemicals and initiating
protective reflexes are found along the mammalian respiratory tract. Studies in mice …

The diffuse chemosensory system (DCS) of the respiratory apparatus is composed of solitary
chemosensory cells (SCCs) that resemble taste cells but are not organized in end organs …

Background Chemical irritation of airway mucosa elicits a variety of reflex responses such as
coughing, apnea, and laryngeal closure. Inhaled irritants can activate either chemosensitive …

The mammalian airways are sensitive to inhaled stimuli, and airway diseases are
characterized by hypersensitivity to volatile stimuli, such as perfumes, industrial solvents …

The nasal epithelium houses a population of solitary chemosensory cells (SCCs). SCCs
express bitter taste receptors and taste transduction signaling components and are …

Background Solitary chemosensory cells (SCCs) are specialized cells in the respiratory
epithelium that respond to noxious chemicals including bacterial signaling molecules. SCCs …

Specialized epithelial cells of the respiratory tract have been termed “solitary chemosensory
cells” based upon the expression of components of the canonical sweet, umami and bitter …

Organisms have developed cellular" antennas" to sense, interpret, and integrate
environmental stimuli. In a recent issue of Science, Sui et al.(2018) demonstrate that discrete …

Tracheal brush cells are cholinergic chemosensory epithelial cells poised to transmit signals
from the airway lumen to the immune and nervous systems. They are part of a family of …

Background The main olfactory epithelium (MOE) in the nasal cavity detects a variety of air
borne molecules that provide information regarding the presence of food, predators and …