Background Ketamine has been established as efficacious in adults living with Treatment-
resistant Depression (TRD). Toward providing a quantifiable estimate of the clinical …

Objective Ketamine has demonstrated rapid and significant antidepressant effects in
patients with treatment resistant depression (TRD). Herein, we conducted a systematic …

Abstract Background and Aims Ketamine and esketamine have garnered interest in both
psychiatric research and clinical practice for treatment-resistant depression (TRD). In this …

Ketamine is a promising therapeutic option in treatment-resistant depression (TRD). The
acute efficacy of ketamine in TRD has been demonstrated in replicated randomised …

Introduction Ketamine treatment is capable of significant and rapid symptom improvement in
adults with treatment-resistant depression (TRD). A limitation of ketamine treatment in TRD …

Objective: Ketamine has demonstrated rapid antidepressant effects in patients with
treatment-resistant depression (TRD); however, the safety and tolerability of ketamine in this …

Background Though intravenous (IV) ketamine and intranasal (IN) esketamine are noted to
be efficacious for treatment-resistant depression (TRD), access to each of these treatments …

Introduction: Few studies have been published to date exploring the effectiveness of
ketamine for treatment-resistant depression (TRD) in large clinical samples. We report on …

Background Sub-anaesthetic administration of ketamine is an emerging practice in patients
presenting treatment resistant depression (TRD), however several outstanding questions …

Background Ketamine and its enantiomers have recently been highlighted as one of the
most effective therapeutic options in refractory depression. However, racemic ketamine and …