No evidence that soluble TACI induces signalling via membrane-expressed BAFF and APRIL in myeloid cells
J Nys, CR Smulski, A Tardivel, L Willen, C Kowalczyk… - PLoS …, 2013 - journals.plos.org
Myeloid cells express the TNF family ligands BAFF/BLyS and APRIL, which exert their
effects on B cells at different stages of differentiation via the receptors BAFFR, TACI …
effects on B cells at different stages of differentiation via the receptors BAFFR, TACI …
The role of APRIL and BAFF in lymphocyte activation
P Schneider - Current opinion in immunology, 2005 - Elsevier
The TNF family ligands BAFF (also called BLyS) and APRIL regulate lymphocyte survival
and activation. BAFF binds to three receptors, BAFF-R, TACI and BCMA, whereas APRIL …
and activation. BAFF binds to three receptors, BAFF-R, TACI and BCMA, whereas APRIL …
To switch or not to switch–the opposing roles of TACI in terminal B cell differentiation
U Salzer, S Jennings… - European journal of …, 2007 - Wiley Online Library
The TNF superfamily ligands BAFF and APRIL and their three receptors BAFFR, BCMA, and
TACI comprise a network that is critically involved in the development and function of …
TACI comprise a network that is critically involved in the development and function of …
TACI, an enigmatic BAFF/APRIL receptor, with new unappreciated biochemical and biological properties
F Mackay, P Schneider - Cytokine & growth factor reviews, 2008 - Elsevier
BAFF is a B cell survival factor that binds to three receptors BAFF-R, TACI and BCMA. BAFF-
R is the receptor triggering naïve B cell survival and maturation while BCMA supports the …
R is the receptor triggering naïve B cell survival and maturation while BCMA supports the …
TACI, unlike BAFF-R, is solely activated by oligomeric BAFF and APRIL to support survival of activated B cells and plasmablasts
C Bossen, TG Cachero, A Tardivel… - Blood, The Journal …, 2008 - ashpublications.org
The cytokine BAFF binds to the receptors TACI, BCMA, and BAFF-R on B cells, whereas
APRIL binds to TACI and BCMA only. The signaling properties of soluble trimeric BAFF …
APRIL binds to TACI and BCMA only. The signaling properties of soluble trimeric BAFF …
BAFF AND APRIL: a tutorial on B cell survival
F Mackay, P Schneider, P Rennert… - Annual review of …, 2003 - annualreviews.org
BAFF, a member of the TNF family, is a fundamental survival factor for transitional and
mature B cells. BAFF overexpression leads to an expanded B cell compartment and …
mature B cells. BAFF overexpression leads to an expanded B cell compartment and …
T cell costimulation by the TNF ligand BAFF
B Huard, P Schneider, D Mauri, J Tschopp… - The Journal of …, 2001 - journals.aai.org
The TNF ligand family member B cell-activating factor belonging to TNF family (BAFF, also
called Blys, TALL-1, zTNF-4, or THANK) is an important survival factor for B cells. In this …
called Blys, TALL-1, zTNF-4, or THANK) is an important survival factor for B cells. In this …
Mechanism of BLyS action in B cell immunity
RKG Do, S Chen-Kiang - Cytokine & growth factor reviews, 2002 - Elsevier
The B lymphocyte stimulator (BLyS), also known as BAFF, THANK, TALL-1 and zTNF4, is
the most recent addition to the tumor necrosis factor family (TNF) ligands and has a unique …
the most recent addition to the tumor necrosis factor family (TNF) ligands and has a unique …
Cracking the BAFF code
F Mackay, P Schneider - Nature reviews immunology, 2009 - nature.com
The tumour necrosis factor (TNF) family members B cell activating factor (BAFF) and APRIL
(a proliferation-inducing ligand) are crucial survival factors for peripheral B cells. An excess …
(a proliferation-inducing ligand) are crucial survival factors for peripheral B cells. An excess …
Signal Transduction by Receptors for BAFF and APRIL
The cytokines B-cell-activating factor of the TNF family (BAFF) and A proliferation-inducing
ligand (APRIL) stimulate several of the major signaling cascades responsible for B-cell …
ligand (APRIL) stimulate several of the major signaling cascades responsible for B-cell …