Twin studies reveal specific imbalances in the mucosaassociated microbiota of patients with ileal Crohn's disease
Background Large interindividual variation in the composition of the intestinal microbiota
between unrelated individuals has made it challenging to identify specific aspects of …
between unrelated individuals has made it challenging to identify specific aspects of …
Siblings of patients with Crohn's disease exhibit a biologically relevant dysbiosis in mucosal microbial metacommunities
Objective To determine the existence of mucosal dysbiosis in siblings of patients with
Crohn's disease (CD) using 454 pyrosequencing and to comprehensively characterise and …
Crohn's disease (CD) using 454 pyrosequencing and to comprehensively characterise and …
Molecular analysis of the gut microbiota of identical twins with Crohn's disease
J Dicksved, J Halfvarson, M Rosenquist… - The ISME …, 2008 - academic.oup.com
Increasing evidence suggests that a combination of host genetics and the composition of the
gut microbiota are important for development of Crohn's disease (CD). Our aim was to study …
gut microbiota are important for development of Crohn's disease (CD). Our aim was to study …
A pyrosequencing study in twins shows that gastrointestinal microbial profiles vary with inflammatory bowel disease phenotypes
BACKGROUND & AIMS:: The composition of the gastrointestinal microbiota is thought to
have an important role in the etiology of inflammatory bowel diseases (IBDs) such as …
have an important role in the etiology of inflammatory bowel diseases (IBDs) such as …
Highlighting new phylogenetic specificities of Crohn's disease microbiota
S Mondot, S Kang, JP Furet… - Inflammatory bowel …, 2011 - academic.oup.com
Background Recent studies suggest that gastrointestinal (GI) microbes play a part in the
pathogenesis of Crohn's disease (CD). Methods Fecal samples were collected from 16 …
pathogenesis of Crohn's disease (CD). Methods Fecal samples were collected from 16 …
Abnormal microbiota composition in the ileocolonic mucosa of Crohn's disease patients as revealed by polymerase chain reaction-denaturing gradient gel …
M Martinez-Medina, X Aldeguer… - Inflammatory bowel …, 2006 - academic.oup.com
Background Bacteria might play a role in the pathogenesis of Crohn's disease (CD), and
patients harbor a different type and density of gut microbiota compared with normal healthy …
patients harbor a different type and density of gut microbiota compared with normal healthy …
Biodiversity of the mucosa-associated microbiota is stable along the distal digestive tract in healthy individuals and patients with IBD
Background The mucosa-associated microbiota, being very close to the inflammatory
process associated with inflammatory bowel disease (IBD), may have a pathogenic role. We …
process associated with inflammatory bowel disease (IBD), may have a pathogenic role. We …
Twin study indicates loss of interaction between microbiota and mucosa of patients with ulcerative colitis
BACKGROUND & AIMS: Interactions between genetic and environmental factors are
believed to be involved in onset and initiation of inflammatory bowel disease. We analyzed …
believed to be involved in onset and initiation of inflammatory bowel disease. We analyzed …
Dysbiosis of fecal microbiota in Crohn's disease patients as revealed by a custom phylogenetic microarray
Background A custom phylogenetic microarray composed of small subunit ribosomal RNA
probes, representing≈ 500 bacterial species from the human and animal gut, was …
probes, representing≈ 500 bacterial species from the human and animal gut, was …
A modular organization of the human intestinal mucosal microbiota and its association with inflammatory bowel disease
M Tong, X Li, L Wegener Parfrey, B Roth, A Ippoliti… - PloS one, 2013 - journals.plos.org
Abnormalities of the intestinal microbiota are implicated in the pathogenesis of Crohn's
disease (CD) and ulcerative colitis (UC), two spectra of inflammatory bowel disease (IBD) …
disease (CD) and ulcerative colitis (UC), two spectra of inflammatory bowel disease (IBD) …