Disulfide bonds formed by a pair of cysteine residues in the peptides' backbone represent a
certain problem for their sequencing by means of mass spectrometry. As a rule, in …

Our scientific interests involve de novo sequencing of non-tryptic natural amphibian skin
peptides including those with intramolecular S–S bond by means of exclusively mass …

Mass spectrometry faces considerable difficulties in de novo sequencing of long non-tryptic
peptides with S–S bonds. Long disulfide-containing peptides brevinins 1E and 2Ec from frog …

Long disulfide-containing peptides, brevinins 1E and 2Ec, from the skin secretion of the frog
Rana ridibunda were reduced and alkylated with ten novel and three known derivatizing …

Rationale Mass spectrometry has shown itself to be the most efficient tool for the sequencing
of peptides. However, de novo sequencing of novel natural peptides is significantly more …

Tandem mass spectrometry sequencing, as well as Edman sequencing of peptides
belonging to the Rana genus, represents a difficult task due to the presence of a disulfide …

A new tryptophyllin‐like peptide family was found in the skin secretion of the tree frog Hyla
savignyi. Peptides were characterized by database‐independent sequencing strategies and …

Five natural peptides isolated from ranid skin secretions of European frog species of Rana
ridibunda and Rana arvalis (molecular masses 3516, 2674, 2636, 1874, and 1810 Da) were …

A high‐performance liquid chromatography nano‐electrospray ionization Fourier transform
mass spectrometry (HPLC/nanoESI‐FTMS) approach involving recording of collision …

Peptide families are characterized by structural motifs, which often comprise specific post-
translational modifications (PTMs) required for biological activity. In conventional bioactivity …