Early life stress (ELS), such as abuse and neglect during childhood, can lead to psychiatric
disorders in later life. Previous studies have suggested that ELS can cause profound …

Early life stress (ELS) induces long-term phenotypic adaptations that contribute to increased
vulnerability to a host of neuropsychiatric disorders. Epigenetic mechanisms, including DNA …

Both history of early-life stress (ELS) and female sex are associated with increased risk for
depression. The complexity of how ELS interacts with brain development and sex to impart …

Depression is one of the most common mental disorders and has caused an overwhelming
burden on world health. Abundant studies have suggested that early life stress may grant …

Early life adversity (ELA)-including childhood physical, emotional, and sexual abuse, as well
as childhood neglect-is an important predictive factor for negative psychopathology …

Exposure to early life stress (ELS), such as childhood abuse and neglect is a well
established major risk factor for developing psychiatric and behavioral disorders later in life …

Objective Depression is associated with various environmental risk factors such as stress,
childhood maltreatment experiences, and stressful life events. Current approaches to assess …

Throughout the 20th century a body of literature concerning the long-lasting effects of the
early environment was produced. Adverse experiences in early life, or early-life stress (ELS) …

Depression is a devastating psychiatric disorder caused by a combination of genetic
predisposition and life events, mainly exposure to stress. Early life stress (ELS) in particular …

Childhood environment can have a profound impact on brain structure and function.
Epigenetic mechanisms have been shown to play a critical role in adaptive and maladaptive …