Biological Factors Influencing Individual Responses to Propylene Oxide: A Systematic Review of Exogenous Exposure, Endogenous Production and Detoxification

IS Gabashvili - medRxiv, 2024 - medrxiv.org
Objective This systematic review aims to synthesize current knowledge on Propylene Oxide
(PO) in human exhaled breath, examining its presence across various biological matrices …

Cross-sectional and longitudinal associations between propylene oxide exposure and lung function among Chinese community residents: roles of oxidative DNA …

W Liu, L Yu, M Zhou, Z Ye, R Liang, Q Tan, J Song… - Chest, 2023 - Elsevier
Background Toxicologic studies have reported propylene oxide (PO) exposure may harm
the respiratory system, but the association between PO exposure and lung function and …

Propylene Oxide, Lung Function, and Oxidative Stress: What Are the Public Health Implications?

L Dauchet - Chest, 2023 - journal.chestnet.org
In this issue of CHEST, Liu et al 1 report on an association between exposure to propylene
oxide (PO), lung function, and oxidative DNA damage in a cohort of Chinese community …

Organophosphate esters, airway inflammation, and lung function among US participants: A nationally representative cross-sectional study from NHANES, 2011–2012

P Hu, S Ke, A Vinturache, Y Chen, G Ding… - Science of The Total …, 2023 - Elsevier
Background Human beings are widespread exposed to organophosphate esters (OPEs),
but little is known about their effects on respiratory health. Objectives To investigate the …

Concentrations of the propylene metabolite propylene oxide in blood of propylene-exposed rats and humans—a basis for risk assessment

JG Filser, C Hutzler, F Rampf, W Kessler… - Toxicological …, 2008 - academic.oup.com
Propylene (PE) was not carcinogenic in long-term studies in rodents. However, its
biotransformation to propylene oxide (PO) raises questions about a carcinogenic risk. PO …

1, 2-propylene glycol: a biomarker of exposure specific to e-cigarette consumption

T Burkhardt, N Pluym, G Scherer, M Scherer - Separations, 2021 - mdpi.com
Over the past decade, new emerging tobacco and nicotine-delivery products have changed
the tobacco landscape. Especially, electronic cigarettes (ECs) have been suggested to be …

A physiological toxicokinetic model for inhaled propylene oxide in rat and human with special emphasis on the nose

GA Csanády, JG Filser - Toxicological sciences, 2007 - academic.oup.com
Chronic exposure to high concentrations of PO induced inflammation in the respiratory nasal
mucosa (RNM) of rodents and, for concentrations≥ 300 ppm, caused nasal tumors …

Mode of action assessment for propylene dichloride as a human carcinogen

JS Kozal, HN Lynch, J Klapacz, RS Schoeny… - Chemico-Biological …, 2023 - Elsevier
As part of a systematic review of the non-cancer and cancer hazards of propylene dichloride
(PDC), with a focus on potential carcinogenicity in workers following inhalation exposures …

[HTML][HTML] Gas–particle partitioning of organophosphate esters in indoor and outdoor air and its implications for individual exposure

K Liu, H Xiao, Y Zhang, H He, S Li, S Yang… - Environment International, 2023 - Elsevier
The extensive utilization of organophosphate esters (OPEs) has resulted in their widespread
presence in the environment, raising concerns about potential human health risks. In this …

[HTML][HTML] Exposure to organophosphate esters and metabolic syndrome in adults

K Luo, R Zhang, R Aimuzi, Y Wang, M Nian… - Environment …, 2020 - Elsevier
Abstract Background Organophosphate esters (OPEs) are increasingly used as flame
retardants and plasticizers in various products. In vivo and in vitro studies suggest that OPEs …