Super enhanced permeability and retention (SUPR) effects in tumors following near infrared photoimmunotherapy
H Kobayashi, PL Choyke - Nanoscale, 2016 - pubs.rsc.org
To date, the delivery of nano-sized therapeutic agents to cancers largely relies on enhanced
permeability and retention (EPR) effects that are caused by the leaky nature of cancer …
permeability and retention (EPR) effects that are caused by the leaky nature of cancer …
Near infrared photoimmunotherapy of cancer; possible clinical applications
H Wakiyama, T Kato, A Furusawa, PL Choyke… - …, 2021 - degruyter.com
Near-infrared photoimmunotherapy (NIR-PIT) is a new cancer treatment that uses an
antibody-photo-absorber conjugate (APC) composed of a targeting monoclonal antibody …
antibody-photo-absorber conjugate (APC) composed of a targeting monoclonal antibody …
Improved micro-distribution of antibody-photon absorber conjugates after initial near infrared photoimmunotherapy (NIR-PIT)
T Nagaya, Y Nakamura, K Sato, T Harada… - Journal of Controlled …, 2016 - Elsevier
Near infrared photoimmunotherapy (NIR-PIT), a targeted cancer therapy which uses an
antibody-photo absorber conjugate (APC) and near infrared light exposure, dramatically …
antibody-photo absorber conjugate (APC) and near infrared light exposure, dramatically …
[HTML][HTML] Near-infrared photoimmunotherapy: a comparison of light dosing schedules
F Ogata, T Nagaya, Y Nakamura, K Sato, S Okuyama… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Near infrared photoimmunotherapy (NIR-PIT) is a newly-developed cancer therapy in which
a monoclonal antibody is conjugated to a near-infrared photoabsorber, IR700 to form an …
a monoclonal antibody is conjugated to a near-infrared photoabsorber, IR700 to form an …
Markedly enhanced permeability and retention effects induced by photo-immunotherapy of tumors
K Sano, T Nakajima, PL Choyke, H Kobayashi - ACS nano, 2013 - ACS Publications
A major barrier to cancer treatment is the inability to deliver sufficient concentrations of drug
to the tumor without incurring systemic toxicities. Nanomaterials are appealing because they …
to the tumor without incurring systemic toxicities. Nanomaterials are appealing because they …
Quickly evolving near‐infrared photoimmunotherapy provides multifaceted approach to modern cancer treatment
Among modalities of cancer immunotherapy, near‐infrared photoimmunotherapy (NIR‐PIT)
has reached significant preclinical and clinical stages and quickly evolved over the last 5 …
has reached significant preclinical and clinical stages and quickly evolved over the last 5 …
Contrast-enhanced ultrasound imaging for monitoring the efficacy of near-infrared photoimmunotherapy
K Matsuoka, M Yamada, N Fukatsu, K Goto… - …, 2023 - thelancet.com
Background Near-infrared photoimmunotherapy (NIR-PIT) is a promising cancer therapy
combining NIR-light irradiation with an antibody and IR700DX, a light-sensitive substance …
combining NIR-light irradiation with an antibody and IR700DX, a light-sensitive substance …
Near-infrared photoimmunotherapy of cancer
H Kobayashi, PL Choyke - Accounts of chemical research, 2019 - ACS Publications
Conspectus This Account is the first comprehensive review article on the newly developed,
photochemistry-based cancer therapy near-infrared (NIR) photoimmunotherapy (PIT). NIR …
photochemistry-based cancer therapy near-infrared (NIR) photoimmunotherapy (PIT). NIR …
Enhanced permeability and retention effect: A key facilitator for solid tumor targeting by nanoparticles
Exploring the enhanced permeability and retention (EPR) effect through therapeutic
nanoparticles has been a subject of considerable interest in tumor biology. This passive …
nanoparticles has been a subject of considerable interest in tumor biology. This passive …
Near infrared photoimmunotherapy with combined exposure of external and interstitial light sources
Y Maruoka, T Nagaya, K Sato, F Ogata… - Molecular …, 2018 - ACS Publications
Near infrared photoimmunotherapy (NIR-PIT) is a new target-cell-specific cancer treatment
that induces highly selective necrotic/immunogenic cell death after systemic administration …
that induces highly selective necrotic/immunogenic cell death after systemic administration …