Transforming growth factor alpha (TGFα) is a growth factor involved in osteoarthritis (OA).
TGFα induces an OA-like phenotype in articular chondrocytes, by inhibiting matrix synthesis …

Transforming growth factor beta 1 (TGF-β1) is implicated in osteoarthritis. We therefore
studied the role of TGF-β1 signaling in the development of osteoarthritis in a developmental …

Objective TGFβ is a key player in cartilage homeostasis and OA pathology. However, few
data are available on the role of TGFβ signalling in the different OA phenotypes. Here, we …

Osteoarthritis (OA) is a major source of pain and disability worldwide with no effective
medical therapy due to poor understanding of its pathogenesis. Transforming growth factor β …

Transforming growth factor‐β (TGF‐β) has been demonstrated as a potential therapeutic
target in osteoarthritis. However, beneficial effects of TGF‐β supplement and inhibition have …

Objective Transforming growth factor-β (TGFβ) is a pleiotropic cytokine that is central in the
regulation of joint health and disease. Inhibition of TGFβ activity/signaling in experimental …

We have recently identified transforming growth factor alpha (TGFα) as a novel growth factor
involved in the joint disease osteoarthritis. The role of TGFα in normal cartilage and bone …

Objective Transforming growth factor β (TGFβ) signaling plays a complex tissue‐specific and
nonlinear role in osteoarthritis (OA). This study was conducted to determine the osteocytic …

Objective While transforming growth factor β (TGFβ) signaling plays a critical role in
chondrocyte metabolism, the TGFβ signaling pathways and target genes involved in …

Osteoarthritis (OA) is a degenerative joint disorder characterized by the destruction of
articular cartilage, subchondral bone and other joint tissues. Although multiple growth …